Selective cleavage of the C-C bonds of aminoethyl groups, via a multistep pathway, by a pincer iridium complex

被引：29

作者：

Zhang, XW ^{[1
]}

Emge, TJ ^{[1
]}

Ghosh, R ^{[1
]}

Goldman, AS ^{[1
]}

机构：

[1] Rutgers State Univ, Dept Chem, Piscataway, NJ 08854 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2005年 / 127卷 / 23期

关键词：

D O I：

10.1021/ja051300p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A pincer-ligated iridium complex is found to react with N-ethylamines, HN(Et)R (R = cyclohexyl, tert-butyl, ethyl), to give the corresponding iridium isocyanide complexes (PCP)Ir(CH3)(H)(CNR) (PCP = κ3-2,6-(tBu2PCH2)2C6H3). This novel, regioselective C-C bond cleavage reaction occurs readily under mild conditions (25-45 °C). The reaction is shown to proceed via initial dehydrogenation of the amine to give the corresponding imine (N-ethylidenealkylamine). The ethylidene sp2 C-H bond then undergoes addition to iridium, followed by methyl migration. Copyright © 2005 American Chemical Society.

引用

页码：8250 / 8251

页数：2

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