Endogenous hydrogen sulfide as a mediator of vas deferens smooth muscle relaxation

被引：18

作者：

Li, Jingxin ^{[1
,2
]}

Li, Yan ^{[1
,2
]}

Du, Yahui ^{[1
,2
]}

Mou, Kun ^{[3
]}

Sun, Hui ^{[1
,2
]}

Zang, Yuanwei ^{[1
,2
]}

Liu, Chuanyong ^{[1
,2
]}

机构：

[1] Shandong Univ, Sch Med, Dept Physiol, Jinan 250012, Shandong, Peoples R China

[2] Shandong Univ, Key Lab Med Neuroiol, Jinan 250012, Shandong, Peoples R China

[3] Shandong Univ, Qilu Hosp, Dept Pathol, Jinan 250012, Shandong, Peoples R China

来源：

FERTILITY AND STERILITY | 2011年 / 95卷 / 05期

基金：

中国国家自然科学基金;

关键词：

Vas deferens; hydrogen sulfide; cystathionine-beta-synthetase; cystathionine-gamma-lyase; spontaneous contraction; H2S;

D O I：

10.1016/j.fertnstert.2010.11.001

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Cystathionine-lyase and cystathionine-synthase, both H2S-synthesizing enzymes, were functionally expressed in the vas deferens of rat, mice, and human. Endogenous H2S mediated vas deferens smooth muscle relaxation. (Fertil Steril (R) 2011;95:1833-5. (C)2011 by American Society for Reproductive Medicine.)

引用

页码：1833 / 1835

页数：3

共 9 条

[1] Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation [J].

Bianca, Roberta d'Emmanuele di Villa ;

Sorrentino, Raffaella ;

Maffia, Pasquale ;

Mirone, Vincenzo ;

Imbimbo, Ciro ;

Fusco, Ferdinando ;

De Palma, Raffaele ;

Ignarro, Louis J. ;

Cirino, Giuseppe .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (11) :4513-4518

[2] Exogenous hydrogen sulfide (H2S) protects against regional myocardial ischemia-reperfusion injury -: Evidence for a role of KATP channels [J].

Johansen, D ;

Ytrehus, K ;

Baxter, GF .

BASIC RESEARCH IN CARDIOLOGY, 2006, 101 (01) :53-60

[3] Down-regulation of endogenous hydrogen sulfide pathway in pulmonary hypertension and pulmonary vascular structural remodeling induced by high pulmonary blood flow in rats [J].

Li, XH ;

Du, JB ;

Shi, L ;

Li, J ;

Tian, XY ;

Qi, JG ;

Wei, B ;

Jin, HF ;

Tang, CS .

CIRCULATION JOURNAL, 2005, 69 (11) :1418-1424

[4]

Pearson RJ, 2006, CLIN INVEST MED, V29, P146

[5] FAILURE OF EJACULATION WITH INDORAMIN [J].

PENTLAND, B ;

ANDERSON, DA ;

CRITCHLEY, JAJH .

BRITISH MEDICAL JOURNAL, 1981, 282 (6274) :1433-1434

[6] Why and how realizing hypospermia assessment? [J].

Robin, G. ;

Marcelli, F. ;

Mitchell, V. ;

Marchetti, C. ;

Lemaitre, L. ;

Dewailly, D. ;

Leroy-Billiard, M. ;

Rigot, J. -M. .

GYNECOLOGIE OBSTETRIQUE & FERTILITE, 2008, 36 (10) :1035-1042

[7] INFLUENCE OF VAS-DEFERENS MOBILIZATION ON RAT FERTILITY - IMPLICATIONS REGARDING ORCHIOPEXY [J].

SMITH, EM ;

DAHMS, BB ;

ELDER, JS .

JOURNAL OF UROLOGY, 1993, 150 (02) :663-666

[8] H2S as a physiologic vasorelaxant:: Hypertension in mice with deletion of cystathionine γ-lyase [J].

Yang, Guangdong ;

Wu, Lingyun ;

Jiang, Bo ;

Yang, Wei ;

Qi, Jiansong ;

Cao, Kun ;

Meng, Qinghe ;

Mustafa, Asif K. ;

Mu, Weitong ;

Zhang, Shengming ;

Snyder, Solomon H. ;

Wang, Rui .

SCIENCE, 2008, 322 (5901) :587-590

[9] Modulation of endogenous production of H2S in rat tissues [J].

Zhao, WM ;

Ndisang, JF ;

Wang, R .

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2003, 81 (09) :848-853

← 1 →