Brain injury after cardiac arrest: pathophysiology, treatment, and prognosis

被引：257
作者：
Sandroni, Claudio [1 ,2 ]
Cronberg, Tobias [3 ]
Sekhon, Mypinder [4 ]
机构：
[1] Univ Cattolica Sacro Cuore, Inst Anaesthesiol & Intens Care Med, Rome, Italy
[2] Univ Cattolica Sacro Cuore, Dept Intens Care Emergency Med & Anaesthesiol, Fdn Policlin Univ Agostino Gemelli, IRCCS, Largo Francesco Vito 1, I-00168 Rome, Italy
[3] Lund Univ, Skane Univ Hosp, Dept Clin Sci Lund, Neurol, Lund, Sweden
[4] Univ British Columbia, Div Crit Care Med, Dept Med, Vancouver, BC, Canada
来源：
INTENSIVE CARE MEDICINE | 2021年 / 47卷 / 12期
关键词：
Cardiac arrest; Coma; Prognostication; Hypoxia-Ischemia; Brain; EEG; TARGETED TEMPERATURE MANAGEMENT; QUALITY-OF-LIFE; CEREBRAL-BLOOD-FLOW; NEURON-SPECIFIC ENOLASE; INTENSIVE-CARE; COMPUTED-TOMOGRAPHY; COMATOSE PATIENTS; CARDIOPULMONARY-RESUSCITATION; NEUROLOGICAL PROGNOSTICATION; PERFORMANCE CATEGORY;
D O I：
10.1007/s00134-021-06548-2
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
Post-cardiac arrest brain injury (PCABI) is caused by initial ischaemia and subsequent reperfusion of the brain following resuscitation. In those who are admitted to intensive care unit after cardiac arrest, PCABI manifests as coma, and is the main cause of mortality and long-term disability. This review describes the mechanisms of PCABI, its treatment options, its outcomes, and the suggested strategies for outcome prediction.
引用
收藏
页码：1393 / 1414
页数：22
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