Calcitonin

被引：7
作者：
Silverman, SL
机构：
[1] OMC Clin Res Ctr, Beverly Hills, CA 90211 USA
[2] Cedars Sinai Med Ctr, DVA Greater Los Angeles Hlth Care Syst, Los Angeles, CA 90048 USA
[3] Univ Calif Los Angeles, Dept Med, Los Angeles, CA 90024 USA
来源：
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2001年 / 27卷 / 01期
关键词：
D O I：
10.1016/S0889-857X(05)70193-9
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Calcitonin is a polypeptide hormone of thyroid origin that inhibits bone resorption by osteoclasts. Salmon calcitonin is available in injectable form and as nasal spray. At the dose of 200 IU nasal spray QD, salmon calcitonin reduces the risk of vertebral fracture in late postmenopausal women with osteoporosis. Nasal calcitonin produces small increments in bone mass of the spine and modest decreases in bone turnover. No significant effect on non-vertebral fracture has been observed.
引用
收藏
页码：187 / +
页数：11
相关论文
共 45 条
  • [11] LONG-TERM TOLERABILITY OF NASAL SPRAY FORMULATION OF SALMON-CALCITONIN
    FOTI, R
    MARTORANA, U
    BROGGINI, M
    [J]. CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 1995, 56 (04): : 429 - 435
  • [12] AN EFFECTIVE REGIMEN OF INTRANASAL SALMON-CALCITONIN IN EARLY POSTMENOPAUSAL BONE LOSS
    GENNARI, C
    AGNUSDEI, D
    MONTAGNANI, M
    GONNELLI, S
    CIVITELLI, R
    [J]. CALCIFIED TISSUE INTERNATIONAL, 1992, 50 (04) : 381 - 383
  • [13] GENNARI C, 1983, LANCET, V1, P594
  • [14] GENNARI C, 1991, REV CLIN ESP S1, V188, P60
  • [15] LONG-TERM CALCITONIN THERAPY IN POSTMENOPAUSAL OSTEOPOROSIS
    GRUBER, HE
    IVEY, JL
    BAYLINK, DJ
    MATTHEWS, M
    NELP, WB
    SISOM, K
    CHESNUT, CH
    [J]. METABOLISM-CLINICAL AND EXPERIMENTAL, 1984, 33 (04): : 295 - 303
  • [16] BONE DENSITOMETRIC AND HISTOMORPHOMETRIC RESPONSES TO SEQUENTIAL HUMAN PARATHYROID-HORMONE (1-38) AND SALMON-CALCITONIN IN OSTEOPOROTIC PATIENTS
    HODSMAN, AB
    STEER, BM
    FRAHER, LJ
    DROST, DJ
    [J]. BONE AND MINERAL, 1991, 14 (01): : 67 - 83
  • [17] EVIDENCE FOR EFFICACY OF DRUGS AFFECTING BONE METABOLISM IN PREVENTING HIP FRACTURE
    KANIS, JA
    JOHNELL, O
    GULLBERG, B
    ALLANDER, E
    DILSEN, G
    GENNARI, C
    VAZ, AAL
    LYRITIS, GP
    MAZZUOLI, G
    MIRAVET, L
    PASSERI, M
    CANO, RP
    RAPADO, A
    RIBOT, C
    [J]. BRITISH MEDICAL JOURNAL, 1992, 305 (6862) : 1124 - 1128
  • [18] Kraenzlin ME, 1996, CALCIFIED TISSUE INT, V58, P216
  • [19] PREVENTION OF FURTHER BONE MASS-LOSS BY NASAL CALCITONIN IN PATIENTS ON LONG-TERM GLUCOCORTICOID THERAPY FOR ASTHMA - A 2-YEAR FOLLOW-UP-STUDY
    LUENGO, M
    PONS, F
    DEOSABA, MJM
    PICADO, C
    [J]. THORAX, 1994, 49 (11) : 1099 - 1102
  • [20] ANALGESIC EFFECT OF SALMON-CALCITONIN IN OSTEOPOROTIC VERTEBRAL FRACTURES - A DOUBLE-BLIND PLACEBO-CONTROLLED CLINICAL-STUDY
    LYRITIS, GP
    TSAKALAKOS, N
    MAGIASIS, B
    KARACHALIOS, T
    YIATZIDES, A
    TSEKOURA, M
    [J]. CALCIFIED TISSUE INTERNATIONAL, 1991, 49 (06) : 369 - 372
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