Report of the working group for dietary salt reduction of the Japanese society of hypertension: (1) Rationale for salt restriction and salt-restriction target level for the management of hypertension

被引:54
|
作者
Kawano, Yuhei [1 ]
Ando, Katsuyuki [2 ,3 ]
Matsuura, Hideo [3 ]
Tsuchihashi, Takuya [4 ]
Fujita, Toshiro [2 ]
Ueshima, Hirotsup [5 ]
机构
[1] Natl Cardiovasc Ctr, Dept Med, Div Nephrol & Hypertens, Suita, Osaka 5658565, Japan
[2] Univ Tokyo, Fac Med, Dept Internal Med, Tokyo, Japan
[3] Saiseikai Kure Hosp, Dept Internal Med, Kure, Japan
[4] Kyushu Natl Med Ctr, Div Hypertens, Fukuoka, Japan
[5] Shiga Univ Med Sci, Dept Hlth Sci, Otsu, Shiga, Japan
关键词
dietary salt; hypertension; cardiovascular disease; guidelines; large-scale clinical study;
D O I
10.1291/hypres.30.879
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Salt excess is well known to be involved in the pathophysiology of hypertension, and thus restriction of salt intake is widely recommended for management of the disease. Excessive salt intake induces blood pressure (BP)-dependent as well as -independent progression of cardiovascular disease. Although the human body is considered to be adapted to very low salt intake (0.5-3 g/day), restriction to such a low level of salt intake is extremely difficult to accomplish in developed countries. Significant BP reduction has been reported in large-scale clinical studies in which salt intake was decreased to less than 6 g/day, and the results of a meta-analysis have shown that systolic BP was reduced about 1 mmHg with every decrease in salt intake of 1 g/day in hypertensive subjects. Current guidelines for the treatment of hypertension, including Japanese guidelines, recommend dietary salt reduction to 6 g/day or less in hypertensive patients. However, it appears to be fairly difficult to attain this target of salt intake, especially in Japan. There is thus a need for feasible and effective measures to attain this salt restriction target.
引用
收藏
页码:879 / 886
页数:8
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