Site-specific control of distances between gold nanoparticles using phosphorothioate anchors on DNA and a short bifunctional molecular fastener

被引:85
|
作者
Lee, Jung Heon [1 ,4 ]
Wernette, Daryl P. [2 ,4 ]
Yigit, Mehmet V. [3 ,4 ]
Liu, Juewen [2 ,4 ]
Wang, Zidong [1 ,4 ]
Lu, Yi [1 ,2 ,3 ,4 ]
机构
[1] Univ Illinois, Dept Mat Sci & Engn, Urbana, IL 61801 USA
[2] Univ Illinois, Dept Chem, Urbana, IL 61801 USA
[3] Univ Illinois, Ctr Biophys & Computat Biol, Urbana, IL 61801 USA
[4] Univ Illinois, Beckman Inst Adv Sci & Technol, Urbana, IL 61801 USA
关键词
DNA; nanostructures; nanotechnology; self-assembly; surface chemistry;
D O I
10.1002/anie.200702569
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Figure Presented) Going for double gold: Precise control of the positions of and distances between gold nanoparticles (AuNP; gold spheres in picture) is achieved by linking the AuNPs to phosphorothioate-modified DNA (green and red helices) with a bifunctional fastener. The distance between AuNPs is controlled simply by changing the position of the modifications on the DNA template. © 2007 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:9006 / 9010
页数:5
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