KSHV co-infection, a new co-factor for HPV-related cervical carcinogenesis?

被引:0
|
作者
Dai, Lu [1 ,5 ,6 ]
Zhao, Mengmeng [3 ]
Jiang, Wei [4 ]
Lin, Zhen [3 ]
Del Valle, Luis [2 ]
Qin, Zhiqiang [1 ,5 ,6 ]
机构
[1] Louisiana State Univ, Hlth Sci Ctr, Louisiana Canc Res Ctr, Dept Genet, 1700 Tulane Ave, New Orleans, LA 70112 USA
[2] Louisiana State Univ, Hlth Sci Ctr, Louisiana Canc Res Ctr, Dept Pathol, 1700 Tulane Ave, New Orleans, LA 70112 USA
[3] Tulane Univ, Dept Pathol, Tulane Canc Ctr, Hlth Sci Ctr, 1700 Tulane Ave, New Orleans, LA 70112 USA
[4] Med Univ South Carolina, Div Infect Dis, Dept Microbiol & Immunol, Dept Med, 173 Ashley Ave, Charleston, SC 29425 USA
[5] Tongji Univ, Sch Med, East Hosp, Dept Pediat,Res Ctr Translat Med, Shanghai 200120, Peoples R China
[6] Tongji Univ, Sch Med, East Hosp, Key Lab Arrhythmias, Shanghai 200120, Peoples R China
来源
AMERICAN JOURNAL OF CANCER RESEARCH | 2018年 / 8卷 / 11期
基金
中国国家自然科学基金;
关键词
KSHV; HPV; cervical cancer; oncogenic virus; MIGRATION-INHIBITORY FACTOR; HUMAN PAPILLOMA-VIRUS; ORAL KAPOSIS-SARCOMA; HUMAN-HERPESVIRUS-8; DNA; TUMOR-GROWTH; CANCER; EXPRESSION; INFECTION; HIV; MEN;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
High-risk human papillomavirus (HPV) infection is the etiological agent of cervical cancer and some other cancers. Kaposi sarcoma-associated herpesvirus (KSHV) represents a principal causative agent of several human cancers arising in those immunocompromised patients. In fact, KSHV DNA has been detected in the female genital tract, and this virus may share some transmission routes with HPV, although the detection rate of KSHV in cervical samples is very low and the KSHV/HPV co-infection is seldom reported. Currently, it remains unclear about the role of KSHV co-infection in the development of HPV-related neoplasias. In this article, we have summarized the recent finding from clinic and bench indicating KSHV co-infection may represent a co-factor for the development of HPV-related carcinogenesis.
引用
收藏
页码:2176 / 2184
页数:9
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