Metal-Free and Selective Oxidation of Benzylic Alcohols to Aromatic Aldehydes by Hexachloroacetone

被引：3

作者：

Sheikhi, Ehsan ^{[1
]}

Adib, Mehdi ^{[1
]}

Karajabad, Morteza Akherati ^{[1
]}

Rezaei, Narjes ^{[1
]}

机构：

[1] Univ Tehran, Sch Chem, Coll Sci, 16 Azar St,POB 14155-6455, Tehran, Iran

来源：

CHEMISTRYSELECT | 2019年 / 4卷 / 46期

关键词：

chemoselective oxidation; hexachloroacetone; benzylic alcohols; aromatic aldehydes; metal-free; MANGANESE-DIOXIDE OXIDATION; ACID ANHYDRIDE MIXTURES; DIMETHYL-SULFOXIDE; SECONDARY ALCOHOLS; HIGHLY EFFICIENT; AEROBIC OXIDATION; MOLECULAR-OXYGEN; IONIC LIQUID; KETONES; CONVERSION;

D O I：

10.1002/slct.201903790

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A metal-free and selective oxidation of benzylic alcohols which leads to the direct and sustainable production of benzaldehydes has been developed. Compared with former known oxidation reactions like Swern, Pfitzner-Moffatt, Parikh-Doering, and Corey-Kim oxidations, this oxidation approach introduces the HCA as an easily available, safer and less expensive reagent, and also because of the simple removing of chloroform. In addition, it is not necessary to add any metal, acid or base for the oxidation of benzylic alcohols. The oxidation is proceeded in DMSO and also under solvent-free conditions in excellent yields.

引用

页码：13455 / 13458

页数：4

共 69 条

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