Effects of intestinal bacteria on cardiovascular disease

被引：9
作者：
Zhao, Yiyi [1 ]
Chen, Liqun [1 ]
机构：
[1] Fuzhou Univ, Coll Biol Sci & Engn, Fuzhou 350108, Peoples R China
来源：
BIOTECHNOLOGY AND GENETIC ENGINEERING REVIEWS | 2022年 / 38卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Intestinal bacteria; cardiovascular disease; mechanism of action; metabolic products; CHAIN FATTY-ACIDS; NITRIC-OXIDE PRODUCTION; INDOXYL SULFATE; GUT MICROBIOTA; PHENOLIC-COMPOUNDS; HYDROGEN-SULFIDE; OXIDATIVE STRESS; ENDOTHELIAL DYSFUNCTION; UREMIC TOXIN; IN-VITRO;
D O I：
10.1080/02648725.2022.2074696
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
In the long process of human evolution, the Intestinal Bacteria has become intimately related to human health, producing many metabolites in the intestines that can affect cardiovascular disease. Today, the incidence of cardiovascular disease is rising, its treatment is becoming increasingly important, and new therapeutic targets are needed. Here we describe the effects of trimethylamine oxide (TMAO), lipid metabolism, phenolic compounds, indole sulfate (IS), oleuropein (OL), and hydroxytyrosol (HT) on atherosclerosis, heart failure, hypertension, and other cardiovascular diseases, as well as their mechanism of action. This study provides new ideas, new methods, and new directions for the treatment of cardiovascular disease.
引用
收藏
页码：270 / 287
页数：18
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