Readily available new pyridyl alcohols derived from D-glucose as ligands for the enantioselective addition of diethylzinc to aldehydes

被引：15
作者：
Huang, HM [1 ]
Zheng, Z [1 ]
Chen, HL [1 ]
Bai, CM [1 ]
Wang, JW [1 ]
机构：
[1] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China
来源：
TETRAHEDRON-ASYMMETRY | 2003年 / 14卷 / 10期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1016/S0957-4166(03)00212-X
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A series of new chiral ligands derived from D-glucose has been synthesized and applied in the enantioselective addition of diethylzinc to aldehydes. Up to 94.1% e.e. was obtained in the ethylation reactions. In contrast to the ligands derived from D-fructose, ligands derived from D-glucose gave the opposite asymmetric induction. (C) 2003 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：1285 / 1289
页数：5
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