The Stille cross coupling reactions on solid support.: Link to solution phase directed ortho metalation.: An ester linker approach to styryl, biaryl and heterobiaryl carboxylic acids

被引：52

作者：

Chamoin, S ^{[1
]}

Houldsworth, S ^{[1
]}

Snieckus, V ^{[1
]}

机构：

[1] Univ Waterloo, Guelph Waterloo Ctr Grad Work Chem, Waterloo, ON N2L 3G1, Canada

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 24期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/S0040-4039(98)00778-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of the titled compounds by Stille cross coupling on Merrifield resin - linked halo benzoates with stannanes followed by LiOH hydrolysis is reported. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：4175 / 4178

页数：4

共 18 条

[1] Parallel synthesis of tamoxifen and derivatives on solid support via resin capture [J].

Brown, SD ;

Armstrong, RW .

JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (21) :7076-7077

[2] The Suzuki-Miyaura cross coupling reactions on solid support.: Link to solution phase directed ortho metalation.: The Leznoff acetal linker approach to biaryl and heterobiaryl aldehydes [J].

Chamoin, S ;

Houldsworth, S ;

Kruse, CG ;

Bakker, WI ;

Snieckus, V .

TETRAHEDRON LETTERS, 1998, 39 (24) :4179-4182

[3] FORMATION OF CARBON-CARBON BOND ON SOLID SUPPORT - APPLICATION OF THE STILLE REACTION [J].

DESHPANDE, MS .

TETRAHEDRON LETTERS, 1994, 35 (31) :5613-5614

[4] Solid-phase synthesis of indoles using the palladium-catalysed coupling of alkynes with iodoaniline derivatives. [J].

Fagnola, MC ;

Candiani, I ;

Visentin, G ;

Cabri, W ;

Zarini, F ;

Mongelli, N ;

Bedeschi, A .

TETRAHEDRON LETTERS, 1997, 38 (13) :2307-2310

[5] SOLID-PHASE SYNTHESIS OF BIARYLS VIA THE STILLE REACTION [J].

FORMAN, FW ;

SUCHOLEIKI, I .

JOURNAL OF ORGANIC CHEMISTRY, 1995, 60 (03) :523-528

[6] BIARYL SYNTHESIS VIA SUZUKI COUPLING ON A SOLID SUPPORT [J].

FRENETTE, R ;

FRIESEN, RW .

TETRAHEDRON LETTERS, 1994, 35 (49) :9177-9180

[7] Organic chemistry on solid supports [J].

Fruchtel, JS ;

Jung, G .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1996, 35 (01) :17-42

[8] REMOTE AROMATIC METALATION - AN ANIONIC FRIEDEL-CRAFTS EQUIVALENT FOR THE REGIOSELECTIVE SYNTHESIS OF CONDENSED FLUORENONES FROM BIARYL AND META-TERARYL 2-AMIDES [J].

FU, JM ;

ZHAO, BP ;

SHARP, MJ ;

SNIECKUS, V .

JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (05) :1683-1685

[9] APPLICATIONS OF COMBINATORIAL TECHNOLOGIES TO DRUG DISCOVERY .1. BACKGROUND AND PEPTIDE COMBINATORIAL LIBRARIES [J].

GALLOP, MA ;

BARRETT, RW ;

DOWER, WJ ;

FODOR, SPA ;

GORDON, EM .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (09) :1233-1251

[10] Solid-phase Suzuki coupling for C-C bond formation [J].

Guiles, JW ;

Johnson, SG ;

Murray, WV .

JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (15) :5169-5171

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