Association of Autism Spectrum Disorder with Obsessive-Compulsive and Attention-Deficit/Hyperactivity Traits and Response Inhibition in a Community Sample

被引：19
作者：
van der Plas, Ellen [1 ,2 ]
Dupuis, Annie [1 ,3 ]
Arnold, Paul [2 ,4 ,5 ]
Crosbie, Jennifer [1 ]
Schachar, Russell [1 ,2 ]
机构：
[1] Hosp Sick Children, Dept Psychiat, 555 Univ Ave, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Dept Psychiat, 250 Coll St, Toronto, ON M5T 1R8, Canada
[3] Univ Toronto, Dalla Lana Sch Publ Hlth, 563 Spadina Crescent, Toronto, ON M5S 2J7, Canada
[4] Peter Gilgan Ctr Res & Learning, Program Genet & Genome Biol, 686 Bay St, Toronto, ON M5G 0A4, Canada
[5] Univ Calgary, Mathison Ctr Mental Hlth Res & Educ, 3280 Hosp Dr NW, Calgary, AB T2N 4Z6, Canada
来源：
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS | 2016年 / 46卷 / 09期
基金：
加拿大健康研究院;
关键词：
Autism; Attention/deficits hyperactivity disorder; Obsessive compulsive disorder; Familial; Traits; Community sample; DEFICIT HYPERACTIVITY DISORDER; PSYCHIATRIC-DISORDERS; REPETITIVE BEHAVIORS; SELECTION BIAS; CHILDREN; ADHD; PSYCHOPATHOLOGY; COMORBIDITY; METAANALYSIS; ADOLESCENTS;
D O I：
10.1007/s10803-016-2853-y
中图分类号：
B844 [发展心理学（人类心理学）];
学科分类号：
040202 ;
摘要：
We examined co-occurrence of autism spectrum disorder (ASD) with (traits of) attention-deficit/hyperactivity (ADHD), obsessive-compulsive (OCD) and inhibition deficits in a community sample (n = 16,676) and tested whether having a sibling with ASD manifested in increased features of ADHD, OCD or inhibition deficits. Individuals with ASD had increased ADHD and OCD traits compared with individuals without ASD. Individuals with a sibling with ASD exhibited more ADHD traits than did individuals whose sibling did not have ASD. The "sibling effect" on manifestation of ADHD traits was observed in individuals with and without ASD. Having a sibling with ASD did not affect OCD traits. Inhibition was impaired in individuals with ASD who had a sibling with ASD only.
引用
收藏
页码：3115 / 3125
页数：11
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