Cardiovascular Comorbidities in Chronic Obstructive Pulmonary Disease (COPD)Current Considerations for Clinical Practice

被引:52
作者
Trinkmann, Frederik [1 ]
Saur, Joachim [1 ]
Borggrefe, Martin [1 ,2 ]
Akin, Ibrahim [1 ,2 ]
机构
[1] Heidelberg Univ, Univ Med Ctr Mannheim, Med Fac Mannheim, Dept Med 1,Cardiol Angiol Pulm & Intens Care, D-68167 Mannheim, Germany
[2] Heidelberg Univ, Univ Med Ctr Mannheim, Med Fac Mannheim, DZHK German Ctr Cardiovasc Res, Partner Site Mannheim, D-68167 Mannheim, Germany
关键词
COPD; comorbidities; cardiovascular; diagnostics; therapy; SYSTOLIC BLOOD-PRESSURE; PERCUTANEOUS CORONARY INTERVENTION; RENIN-ANGIOTENSIN SYSTEM; SUDDEN CARDIAC DEATH; ALL-CAUSE MORTALITY; ATRIAL-FIBRILLATION; HEART-FAILURE; MYOCARDIAL-INFARCTION; ESC GUIDELINES; BETA-BLOCKERS;
D O I
10.3390/jcm8010069
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In patients with chronic obstructive pulmonary disease (COPD), cardiovascular comorbidities are highly prevalent and associated with considerable morbidity and mortality. This coincidence is increasingly seen in context of a cardiopulmonary continuum rather than being simply attributed to shared risk factors such as cigarette smoking. Overlapping symptoms such as dyspnea or chest pain lead to a worse prognosis due to missed concomitant diagnoses. Moreover, medication is often withheld as a result of unfounded concerns about side effects. Despite the frequent coincidence, current guidelines are still mostly restricted to the management of the individual disease. Future diagnostic and therapeutic strategies should therefore be guided by an integrative perspective as well as a refined phenotyping of disease entities.
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页数:14
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