Numerical investigation of novel microwave applicators based on zero-order mode resonance for hyperthermia treatment of cancer

被引：11

作者：

Vrba, David ^{[1
]}

Vrba, Jan ^{[1
]}

Rodrigues, Dario B. ^{[2
]}

Stauffer, Paul ^{[2
]}

机构：

[1] Czech Tech Univ, Fac Biomed Engn, Zikova 4, Prague 16636, Czech Republic

[2] Thomas Jefferson Univ, Radiat Oncol Dept, Bodine Canc Ctr, 111 S 11th St, Philadelphia, PA 19107 USA

来源：

JOURNAL OF THE FRANKLIN INSTITUTE-ENGINEERING AND APPLIED MATHEMATICS | 2017年 / 354卷 / 18期

关键词：

ANTENNA;

D O I：

10.1016/j.jfranklin.2016.10.044

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

This paper characterizes three novel microwave applicators based on zero-order mode resonators for use in hyperthermia treatment of cancer. The radiation patterns are studied with numerical simulations in muscle tissue-equivalent model at 434 MHz. The relative performance of the applicators is compared in terms of reflection coefficient, current distribution, power deposition (SAR) pattern, effective field size in 2D and 3D tissue volumes, and penetration depth. One particular configuration generated the most uniform SAR pattern, with 25% SAR covering 84% of the treatment volume extending to 1 cm depth under the aperture, while remaining above 58% coverage as deep as 3 cm under the aperture. Recommendations are made to further optimize this structure. (C) 2016 The Franklin Institute. Published by Elsevier Ltd. All rights reserved.

引用

页码：8734 / 8746

页数：13

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