Optimization of image quality and accuracy of low iodine concentration quantification as function of dose level and reconstruction algorithm for abdominal imaging using dual-source CT: A phantom study

被引：20
作者：
Dabli, Djamel [1 ]
Frandon, Julien [1 ]
Belaouni, Asmaa [1 ]
Akessoul, Philippe [1 ]
Addala, Takieddine [1 ]
Berny, Laure [1 ]
Beregi, Jean-Paul [1 ]
Greffer, Joel [1 ]
机构：
[1] Univ Montpellier, Dept Med Imaging, CHU Nimes, Med Imaging Grp Nimes,EA 2994, Nimes, France
来源：
DIAGNOSTIC AND INTERVENTIONAL IMAGING | 2022年 / 103卷 / 01期
关键词：
Dual-energy CT; Iodine quantification; Monochromatic images; Iterative reconstruction; ENERGY CT; COMPUTED-TOMOGRAPHY; PERFORMANCE; DIAGNOSIS; CELL; KV;
D O I：
10.1016/j.diii.2021.08.004
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
Purpose: The purpose of this study was to assess the impact of advanced modeled iterative reconstruction (ADMIRE) algorithm and dose levels on the accuracy of Hounsfield unit (HU) measurement, image noise and contrast-to-noise ratio (CNR) in virtual monochromatic images (VMIs) with low iodine concentrations, and the accuracy of iodine quantification. Materials and methods: A CT phantom was scanned with dual-source CT using abdomen-pelvis examination parameters at four dose levels: 5, 8, 11 and 20 mGy. Images were reconstructed using filtered-back projection (FBP) and ADMIRE levels 3 and 5 (A3-A5). HU accuracy was assessed calculating the root-mean-square deviation (RMSDHU). Image noise and CNR were computed on VMIs at 40/50/60/70 keV for 4 iodine inserts with 0.5, 1, 2 and 5 mg/mL concentrations. Accuracy of iodine quantification was assessed by the RMSDiodine and iodine bias (IB). Results: The RMSDHU decreased significantly as the dose levels increased compared to 5 mGy, except for 8 mGy with A3 (P = 0.380) and with A5 level (P = 0.945). Noise increased by 63.0 +/- 3.0 (standard deviation [SD])% from 20 mGy to 5 mGy. Noise decreased significantly by -53.8 +/- 0.9 (SD) % with A5 compared to FBP. The CNR decreased by -43.1 +/- 6.5 (SD)% from 20 mGy to 5 mGy. It increased using ADMIRE, and as the ADMIRE levels increased. The RMSDiodine and IB decreased as the dose level increased, and this was similar for all reconstruction types. Conclusion: ADMIRE strongly improves image quality in VMIs and slightly improves HU accuracy but does not affect the accuracy of iodine quantification. (c) 2021 Societe francaise de radiologie. Published by Elsevier Masson SAS. All rights reserved.
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页码：31 / 40
页数：10
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