Disrupted computations of social control in individuals with obsessive-compulsive and misophonia symptoms

被引:7
作者
Banker, Sarah M. [1 ,4 ]
Na, Soojung [1 ]
Beltran, Jacqueline [1 ,4 ]
Koenigsberg, Harold W. [2 ,7 ]
Foss-Feig, Jennifer H. [2 ,4 ,5 ]
Gu, Xiaosi [1 ,2 ,3 ,6 ]
Schiller, Daniela [1 ,2 ,3 ,6 ]
机构
[1] Icahn Sch Med Mt Sinai, Nash Family Dept Neurosci, New York, NY 10029 USA
[2] Icahn Sch Med Mt Sinai, Dept Psychiat, New York, NY 10029 USA
[3] Icahn Sch Med Mt Sinai, Friedman Brain Inst, New York, NY 10029 USA
[4] Icahn Sch Med Mt Sinai, Seaver Autism Ctr Res & Treatment, New York, NY 10029 USA
[5] Icahn Sch Med Mt Sinai, Mindich Child Hlth & Dev Inst, New York, NY 10029 USA
[6] Icahn Sch Med Mt Sinai, Ctr Computat Psychiat, New York, NY 10029 USA
[7] James J Peters VA Med Ctr, Bronx, NY 10468 USA
关键词
PERCEIVED CONTROL; RELIABILITY; DISORDERS; SCALE; VALIDATION; VALIDITY;
D O I
10.1016/j.isci.2022.104617
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Misophonia is a disorder in which certain sounds produced by other people lead to intense negative reactions. It remains unknown how misophonia relates to other psychiatric conditions or impairments. To identify latent constructs under-lying symptoms, we conducted a factor analysis consisting of items from ques-tionnaires assessing symptoms of misophonia and other psychiatric conditions. One thousand forty-two participants completed the questionnaires and a social exchange task in which they either could (''controllable'') or could not (''uncon-trollable'') influence future monetary offers from other people. Misophonia and obsessive-compulsive (OC) symptoms loaded onto the same factor. Compared with individuals with low Miso-OC factor scores, individuals with high scores reported higher perceived controllability of their social interactions during the uncontrollable condition and stronger aversion to social norm violations in the un-controllable compared with the controllable condition. Together, these results suggest misophonia, and OC symptoms share a latent psychiatric dimension char-acterized by aberrant computations of social controllability.
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页数:16
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