Iodine mediated nitrosation of imidazo[1,5-a]N-heteroarenes using TBN (tBuONO) reagent

被引：1

作者：

Sandeep, Mummadi ^{[1
,2
]}

Muzaffar-ur-Rehman, Md ^{[1
]}

Chahal, Kapil ^{[1
,2
]}

Reddy, Kallu Rajender ^{[1
,2
]}

机构：

[1] CSIR Indian Inst Chem Technol, Catalysis & Fine Chem Div, Hyderabad 500007, India

[2] Acad Sci & Innovat Res AcSIR, Ghaziabad 201002, UP, India

来源：

TETRAHEDRON LETTERS | 2021年 / 82卷

关键词：

Nitrosation; TBN; Iodine; Imidazo[1; 5-a]N-heteroarenes; TERT-BUTYL NITRITE; ONE-POT SYNTHESIS; C-H; ENANTIOSELECTIVE SYNTHESIS; ARYL FORMAMIDES; FACILE ACCESS; METAL; NITROSOARENES; RADICALS; AMINES;

D O I：

10.1016/j.tetlet.2021.153401

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An iodine mediated regio-selective nitrosation of imidazo[1,5-a]N-heteroarenes is reported using TBN as nitroso source. This method afford synthetically useful and medicinally interesting 3-nitroso imidazo [1,5-a]N-heteroarenes in moderate to good yields with good functional group tolerance. Further, this reaction could applicable on gram-scale level synthesis. (C) 2021 Elsevier Ltd. All rights reserved.

引用

页数：6

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