High-performance extraction of alkaloids using aqueous two-phase systems with ionic liquids

被引:190
作者
Freire, Mara G. [1 ]
Neves, Catarina M. S. S. [2 ]
Marrucho, Isabel M. [1 ]
Lopes, Jose N. Canongia [1 ]
Rebelo, Luis Paulo N. [1 ]
Coutinho, Joao A. P. [2 ]
机构
[1] UNL, Inst Tecnol Quim & Biol, P-2780901 Oeiras, Portugal
[2] Univ Aveiro, CICECO, Dept Quim, P-3810193 Aveiro, Portugal
关键词
BIPHASIC SYSTEMS; SALTING-OUT; PRECIPITATION; PROTEINS; WATER;
D O I
10.1039/c0gc00179a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Ionic-liquid-based aqueous two-phase systems are great candidates for the replacement of volatile organic compounds in typical liquid-liquid extractions. This work shows clear evidence for the complete extraction of alkaloids such as caffeine and nicotine using a single-step procedure.
引用
收藏
页码:1715 / 1718
页数:4
相关论文
共 27 条
[1]  
Albertsson P., 1986, Partitioning of Cell Particles and Macromolecules, DOI [10.1002/cbf.290050311, DOI 10.1002/CBF.290050311]
[2]  
CHAMBRLAIN J, 1995, ANAL DRUGS BIOL FLUI, pCH10
[3]   Carbohydrates-tailored phase tunable systems composed of ionic liquids and water [J].
Chen, Yuhaun ;
Wang, Yige ;
Cheng, Qingyan ;
Liu, Xiaoli ;
Zhang, Suojiang .
JOURNAL OF CHEMICAL THERMODYNAMICS, 2009, 41 (09) :1056-1059
[4]  
COSTILL DL, 1978, MED SCI SPORT EXER, V10, P155
[5]   (Extraction of biomolecules using) aqueous biphasic systems formed by ionic liquids and aminoacids [J].
Dominguez-Perez, Montserrat ;
Tome, Luciana I. N. ;
Freire, Mara G. ;
Marrucho, Isabel M. ;
Cabeza, Oscar ;
Coutinho, Joao A. P. .
SEPARATION AND PURIFICATION TECHNOLOGY, 2010, 72 (01) :85-91
[6]   Extraction of proteins from biological fluids by use of an ionic liquid/aqueous two-phase system [J].
Du, Zhuo ;
Yu, Yong-Liang ;
Wang, Jian-Hua .
CHEMISTRY-A EUROPEAN JOURNAL, 2007, 13 (07) :2130-2137
[7]  
Essig D, 1980, INT J SPORTS MED, V1, P86, DOI DOI 10.1055/S-2008-1034637
[8]  
FLENKER U, 2001, EUROPEAN J SPORT SCI, V1, P1
[9]   1H NMR and Molecular Dynamics Evidence for an Unexpected Interaction on the Origin of Salting-In/Salting-Out Phenomena [J].
Freire, Mara G. ;
Neves, Catarina M. S. S. ;
Silva, Artur M. S. ;
Santos, Luis M. N. B. F. ;
Marrucho, Isabel M. ;
Rebelo, Luis P. N. ;
Shah, Jindal K. ;
Maginn, Edward J. ;
Coutinho, Joao A. P. .
JOURNAL OF PHYSICAL CHEMISTRY B, 2010, 114 (05) :2004-2014
[10]   Ion Specific Effects on the Mutual Solubilities of Water and Hydrophobic Ionic Liquids [J].
Freire, Mara G. ;
Carvalho, Pedro J. ;
Silva, Artur M. S. ;
Santos, Luis M. N. B. F. ;
Rebelo, Luis P. N. ;
Marrucho, Isabel M. ;
Coutinho, Joao A. P. .
JOURNAL OF PHYSICAL CHEMISTRY B, 2009, 113 (01) :202-211