Overcoming erlotinib resistance with STAT3 inhibition in pancreatic cancer

被引：3
|
作者：
Salzberg, Matthew Philip
Merchant, Nipun B.
机构：
[1] Univ Miami, Jackson Mem Hosp, Sylvester Comprehens Canc Ctr, Miller Sch Med, Miami, FL 33136 USA
[2] Univ Miami, Med Ctr, Miami, FL USA
来源：
JOURNAL OF CLINICAL ONCOLOGY | 2017年 / 35卷 / 04期
关键词：
D O I：
10.1200/JCO.2017.35.4_suppl.304
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
304
引用
收藏
页数：1
相关论文
共 50 条
  • [41] AdipoRon suppresses ERK and STAT3 to inhibit pancreatic cancer growth
    Messaggio, Fanuel
    Mendonsa, Alisha M.
    Castellanos, Jason A.
    Roberts, Casey
    Nagathihalli, Nagaraj S.
    Merchant, Nipun B.
    Gorden, Lee D.
    VanSaun, Michael N.
    CANCER RESEARCH, 2016, 76
  • [42] STAT3 is necessary for proliferation and survival in pancreatic cancer initiating cells
    Lin, Li
    Li, Pui-Kai
    Fuchs, James
    Li, Chenglong
    Lin, Jiayuh
    CANCER RESEARCH, 2011, 71
  • [43] Targeting STAT3 by a small molecule suppresses pancreatic cancer progression
    Chen, Huang
    Bian, Aiwu
    Yang, Lian-fang
    Yin, Xuan
    Wang, Jie
    Ti, Chaowen
    Miao, Ying
    Peng, Shihong
    Xu, Shifen
    Liu, Mingyao
    Qiu, Wen-Wei
    Yi, Zhengfang
    ONCOGENE, 2021, 40 (08) : 1440 - 1457
  • [44] Glycogen synthase kinase (GSK)3ß renders pancreatic cancer acquiring resistance to gemcitabine via STAT3 activation
    Domoto, Takahiro
    Takenaka, Satoshi
    Uehara, Masahiro
    Bolidong, Dilireba
    Furukawa, Tatsuhiko
    Miyashita, Tomoharu
    Minamoto, Toshinari
    CANCER SCIENCE, 2022, 113 : 1493 - 1493
  • [45] Inhibition of STAT3 activity with AG490 decreases the invasion of human pancreatic cancer cells in vitro
    Huang, Chen
    Cao, Jun
    Huang, Ke J.
    Zhang, Fang
    Jiang, Tao
    Zhu, Lin
    Qiu, Zheng J.
    CANCER SCIENCE, 2006, 97 (12): : 1417 - 1423
  • [46] Overcoming drug resistance in pancreatic cancer
    Long, Jiang
    Zhang, Yuqing
    Yu, Xianjun
    Yang, Jingxuan
    LeBrun, Drake G.
    Chen, Changyi
    Yao, Qizhi
    Li, Min
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2011, 15 (07) : 817 - 828
  • [47] Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines
    Barton, BE
    Karras, JG
    Murphy, TF
    Barton, A
    Huang, HFS
    MOLECULAR CANCER THERAPEUTICS, 2004, 3 (01) : 11 - 20
  • [48] Overcoming Therapeutic Resistance in Pancreatic Cancer Through Inhibition of Interleukin-1α
    Dosch, A. R.
    Dai, X.
    Mehra, S.
    Willobee, B.
    Messaggio, F.
    Srinivasan, S.
    Nagathihalli, N.
    Merchant, N.
    PANCREAS, 2019, 48 (10) : 1420 - 1421
  • [49] Epigenetic inactivation of PTPRT and sensitivity to STAT3 inhibition in lung cancer
    Sen, Malabika
    Kindsfather, Audrey
    Herman, James G.
    CANCER RESEARCH, 2017, 77
  • [50] STAT3 Inhibition Overcomes Temozolomide Resistance in Glioblastoma by Downregulating MGMT Expression
    Kohsaka, Shinji
    Wang, Lei
    Yachi, Kazuhiro
    Mahabir, Roshan
    Narita, Takuhito
    Itoh, Tamio
    Tanino, Mishie
    Kimura, Taichi
    Nishihara, Hiroshi
    Tanaka, Shinya
    MOLECULAR CANCER THERAPEUTICS, 2012, 11 (06) : 1289 - 1299
12345