Antioxidant action of green tea extract in alloxan-induced diabetic albino rats: An experimental laboratory-based study

被引:0
|
作者
Ali, Ali Hassan A. [1 ,2 ]
Alali, Ali Yaqoub [3 ]
Alhajri, Rasheed A. [3 ]
Aldawsari, Abdulrahman M. [3 ]
AlHeseni, Ammar H. [3 ]
Aldosari, Nasser S. [3 ]
机构
[1] Prince Sattam Bin Abdulaziz Univ, Coll Med, Anat Dept, Alkharj 11942, Saudi Arabia
[2] Al Azhar Univ, Fac Med, Anat Dept, Cairo, Egypt
[3] Prince Sattam Bin Abdulaziz Univ, Coll Med, Al Kharj, Egypt
关键词
Testis; green tea; Antioxidant; alloxan; Albino rat; OXIDATIVE STRESS; LIPID-PEROXIDATION; TESTICULAR DAMAGE; LEYDIG-CELLS; STREPTOZOTOCIN; INSULIN; POLYPHENOLS; CONSUMPTION; CANCER; TESTES;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: Green tea extract can regulate blood sugar and encourage weight loss due to its high antioxidant content. Several studies have shown that green tea extract can improve general health and may help protect against many diseases. Most patients with diabetes are associated with poor fertility. Aim of the work: The present study aimed to evaluate the importance of green tea extract supplementation in reducing metabolic abnormalities associated with alloxan-induced diabetes in male albino rats. Material and Methods: The number of male rats was thirty, weighing 100-110 grams were used in the current study. The rats were divided equally into three groups that included control, diabetic and diabetic took green tea extracts orally (50 mg/Kg/day) for three weeks. To induce diabetes one dose (120 mg/kg) of alloxan was used. Diabetic rats were given "50 mg/kg body weight green tea extracts orally for thirty days twice per day. The morphological and histological structures of the testis were compared in different groups of the rats. Results: It was revealed that the morphological changes of the testis observed in diabetic groups were siginficantly improved after treatment with green tea compared to the control group. Conclusion: These results prove that green tea improves oxidative damage caused by diabetes in the testis of male rats.
引用
收藏
页码:1542 / 1550
页数:9
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