Survival of a Patient with Anaplastic Thyroid Cancer Following Intensity-modulated Radiotherapy and Sunitinib - A Case Report

被引：0
作者：
Schoenfeld, Jonathan D. [1 ,3 ]
Odejide, Oreofe O. [2 ,4 ]
Wirth, Lori J. [2 ]
Chan, Annie W. [1 ]
机构：
[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Radiat Oncol, Boston, MA 02114 USA
[2] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Med Oncol, Boston, MA 02114 USA
[3] Harvard Radiat Oncol Program, Boston, MA USA
[4] Dana Farber Partners CancerCare Hematol Oncol Fel, Boston, MA USA
来源：
ANTICANCER RESEARCH | 2012年 / 32卷 / 05期
关键词：
Anaplastic thyroid carcinoma; chemoradiation; intensity-modulated radiation therapy (IMRT); sunitinib; case report; PROGNOSTIC-FACTORS; TREATMENT OUTCOMES; PHASE-II; CARCINOMA; SURGERY; TRIAL; RADIATION;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Background: Anaplastic: thyroid cancer has a very poor prognosis, especially in patients who have gross residual disease following resection. Case Report: We present the case of a patient with anaplastic thyroid cancer and a significant gross residual disease treated with intensity-modulated radiotherapy with concurrent chemotherapy and sunitinib who had a complete response and remains without evidence of disease more than 18 months after diagnosis. Conclusion: Chemoradiotherapy has an important role in the adjuvant treatment of anaplastic thyroid cancer in selected patients and should be considered when gross residual disease is present following resection. The combined use of radiotherapy and targeted biological agents such as sunitinib may warrant further investigation.
引用
收藏
页码：1743 / 1746
页数：4
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