Regioselective reduction of keto groups in Michael adducts of levoglucosenone and cyclohexanone

被引：2

作者：

Faizullina, Liliya Kh. ^{[1
]}

Galimova, Yuliya S. ^{[1
]}

Khalilova, Yuliya A. ^{[1
]}

Tagirov, Artur R. ^{[1
]}

Salikhov, Shamil M. ^{[1
]}

Valeev, Farid A. ^{[1
]}

机构：

[1] Russian Acad Sci, Ufa Inst Chem, Ufa Fed Res Ctr, Ufa 450054, Russia

来源：

MENDELEEV COMMUNICATIONS | 2022年 / 32卷 / 05期

关键词：

levoglucosenone; cyclohexanone; Michael adduct; regioselective reduction; ketones; LITHIUM;

D O I：

10.1016/j.mencom.2022.09.021

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Conditions for the highly regioselective reduction of the specified keto groups in the Michael adduct of levoglucosenone and cyclohexanone have been developed. Selective reduction of the keto group in the cyclohexanone moiety was performed under the action of lithium metal in NH3/THF system. Reduction of the keto group in the carbohydrate residue was accomplished microbiologically or by refluxing with NaBH(OAc)3 in benzene.

引用

页码：632 / 633

页数：2

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