Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

被引：15

作者：

Koc, Esin ^{[1
]}

Demirel, Nihal ^{[2
]}

Bas, Ahmet Yagmur ^{[2
]}

Isik, Dilek Ulubas ^{[3
]}

Hirfanoglu, Ibrahim Murat ^{[1
]}

Tunc, Turan ^{[4
]}

Sari, Fatma Nur ^{[5
]}

Karatekin, Guner ^{[6
]}

Ozdemir, Ramazan ^{[7
]}

Altunhan, Huseyin ^{[8
]}

Cetinkaya, Merih ^{[9
]}

Ozcan, Beyza ^{[10
]}

Ozkiraz, Servet ^{[11
]}

Calkavur, Sebnem ^{[12
]}

Tekgunduz, Kadir Serafettin ^{[13
]}

Tastekin, Ayhan ^{[14
]}

Ozlu, Ferda ^{[15
]}

Ozyurt, Banu Mutlu ^{[16
]}

Ozdemir, Ahmet ^{[17
]}

Cetinkaya, Bilin ^{[18
]}

Demirelli, Yasar ^{[19
]}

Koklu, Esad ^{[20
]}

Celik, Ulker ^{[21
]}

Tarakci, Nuriye ^{[22
]}

Armangil, Didem ^{[23
]}

Okulu, Emel ^{[24
]}

Narter, Fatma ^{[25
]}

Mutlu, Birgul ^{[26
]}

Mert, Mustafa Kurthan ^{[27
]}

Bulbul, Ali ^{[28
]}

Asker, Huseyin Selim ^{[29
]}

Uygur, Ozgun ^{[30
]}

Uslu, Ilker Sait ^{[31
]}

Ertugrul, Sabahattin ^{[32
]}

Aydemir, Cumhur ^{[33
]}

Celik, Hasan Tolga ^{[34
]}

Kucuktasci, Kazim ^{[35
]}

Arslan, Selda ^{[36
]}

Ergin, Hacer ^{[37
]}

Zenciroglu, Aysegul ^{[38
]}

Yurttutan, Sadik ^{[39
]}

Orman, Aysen ^{[40
]}

Tuncer, Oguz ^{[41
]}

Yasa, Beril ^{[42
]}

Acunas, Betul ^{[43
]}

Takci, Sahin ^{[44
]}

Gokmen, Zeynel ^{[45
]}

Ozkan, Hilal ^{[46
]}

Comert, Serdar ^{[47
]}

Ustun, Nuran ^{[48
]}

机构：

[1] Gazi Univ, Dept Neonatol, Fac Med, Ankara, Turkey

[2] Yildirim Beyazit Univ, Dept Neonatol, Fac Med, Ankara, Turkey

[3] Etlik Zubeyde Hanim Womens Hlth Teaching & Res Ho, Univ Hlth Sci, Dept Neonatol, Ankara, Turkey

[4] Mem Hosp, Div Neonatol, Istanbul, Turkey

[5] Dr Zekai Tahir Burak Womens Hlth Educ & Res Hosp, Univ Hlth Sci, Dept Neonatol, Ankara, Turkey

[6] Zeynep Kamil Matern & Childrens Training & Res Ho, Univ Hlth Sci, Dept Neonatol, Istanbul, Turkey

[7] Inonu Univ, Fac Med, Dept Neonatol, Malatya, Turkey

[8] Necmettin Erbakan Univ, Fac Med, Dept Neonatol, Konya, Turkey

[9] Kanuni Sultan Suleyman Training & Res Hosp, Univ Hlth Sci, Dept Neonatol, Istanbul, Turkey

[10] Konya Educ & Res Hosp, Univ Hlth Sci, Dept Neonatol, Konya, Turkey

[11] Med Pk Hosp, Div Neonatol, Gaziantep, Turkey

[12] Dr Behcet Uz Childrens Hosp, Univ Hlth Sci, Dept Neonatol, Izmir, Turkey

[13] Ataturk Univ, Fac Med, Dept Neonatol, Erzurum, Turkey

[14] Medipol Univ, Fac Med, Dept Neonatol, Istanbul, Turkey

[15] Cukurova Univ, Fac Med, Dept Neonatol, Adana, Turkey

[16] Mersin State Hosp, Div Neonatol, Mersin, Turkey

[17] Erciyes Univ, Fac Med, Dept Neonatol, Kayseri, Turkey

[18] Baskent Univ, Fac Med, Dept Neonatol, Adana, Turkey

[19] Erzurum Nenehatun Matern Hosp, Dept Neonatol, Erzurum, Turkey

[20] Megapk Hosp, Div Neonatol, Kahramanmaras, Turkey

[21] Denizli State Hosp, Div Neonatol, Denizli, Turkey

[22] Dr Faruk Sukan Matern & Childrens Hosp, Dept Neonatol, Konya, Turkey

[23] Yuksek Ihtisas Univ, Fac Med, Dept Neonatol, Ankara, Turkey

[24] Ankara Univ, Fac Med, Dept Neonatol, Ankara, Turkey

[25] Kartal Lutfi Kirdar Educ & Res Hosp, Univ Hlth Sci, Dept Neonatol, Istanbul, Turkey

[26] Doruk Private Hosp, Div Neonatol, Bursa, Turkey

[27] Numune Training & Educ Hosp, Univ Hlth Sci, Dept Neonatol, Adana, Turkey

[28] Sisli Hamidiye Etfal Educ & Res Hosp, Univ Hlth Sci, Dept Neonatol, Istanbul, Turkey

[29] NCR Int Hosp, Div Neonatol, Gaziantep, Turkey

[30] Tepecik Training & Res Hosp, Univ Hlth Sci, Dept Neonatol, Izmir, Turkey

[31] Ondokuz Mayis Univ, Fac Med, Dept Neonatol, Samsun, Turkey

[32] Dicle Univ, Fac Med, Dept Neonatol, Diyarbakir, Turkey

[33] Bulent Ecevit Univ, Fac Med, Dept Neonatol, Zonguldak, Turkey

[34] Hacettepe Univ, Fac Med, Dept Neonatol, Ankara, Turkey

[35] Denizli Saglik Hosp, Div Neonatol, Denizli, Turkey

[36] Mustafa Kemal Univ, Fac Med, Dept Neonatol, Antakya, Turkey

[37] Pamukkale Univ, Fac Med, Dept Neonatol, Denizli, Turkey

[38] Dr Sami Ulus Matern & Childrens Hosp, Univ Hlth Sci, Dept Neonatol, Ankara, Turkey

[39] Kahramanmaras Sutcu Imam Univ, Fac Med, Dept Neonatol, Kahramanmaras, Turkey

[40] Firat Univ, Fac Med, Dept Neonatol, Elazig, Turkey

[41] Yuzuncu Yil Univ, Fac Med, Dept Neonatol, Van, Turkey

[42] Istanbul Univ, Istanbul Fac Med, Dept Neonatol, Istanbul, Turkey

[43] Trakya Univ, Fac Med, Dept Neonatol, Edirne, Turkey

[44] Gaziosmanpasa Univ, Fac Med, Dept Neonatol, Tokat, Turkey

[45] Baskent Univ, Fac Med, Dept Neonatol, Konya, Turkey

[46] Uludag Univ, Fac Med, Dept Neonatol, Bursa, Turkey

[47] Suleymaniye Matern Res & Training Hosp, Univ Hlth Sci, Dept Neonatol, Istanbul, Turkey

[48] Medeniyet Univ, Fac Med, Dept Neonatol, Istanbul, Turkey

[49] Karadeniz Tech Univ, Fac Med, Dept Neonatol, Trabzon, Turkey

[50] Bezmialem Univ, Fac Med, Dept Neonatol, Istanbul, Turkey

来源：

PLOS ONE | 2019年 / 14卷 / 12期

关键词：

BRONCHOPULMONARY DYSPLASIA; NECROTIZING ENTEROCOLITIS; MORBIDITY; MORTALITY; HEALTH; PREMATURITY; INFECTIONS; COUNTRIES; DISTRESS; SEPSIS;

D O I：

10.1371/journal.pone.0226679

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Objective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 and April 30, 2017. The study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of.1500 g were collected for infants who survived. Results Data from 69 NICUs were obtained. The mean birth weight and gestational age were 1137 +/- 245 g and 29 +/- 2.4 weeks, respectively. During the study period, 78% of VLBW infants survived to discharge and 48% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7% of infants, necrotizing enterocolitis in 9.1%, blood culture proven late-onset sepsis (LOS) in 21.1%, blood culture negative LOS in 21.3%, severe intraventricular hemorrhage in 5.4% and severe retinopathy of prematurity in 11.1%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8% of infants. Antenatal steroids were administered to 42.9% of mothers. Conclusion The present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs.

引用

页数：12

共 32 条

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