Photochemical release of nitric oxide from a regenerable, sol-gel encapsulated Ru-salen-nitrosyl complex

被引:47
作者
Bordini, J
Ford, PC
Tfouni, E
机构
[1] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Dept Quim, BR-14040901 Sao Paulo, Brazil
[2] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA
关键词
D O I
10.1039/b507407j
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Light actviation leads to release of NO from a silicate sol-gel material SG-RuNO prepared from the ruthenium complex, [Ru(salen)(OH2)(NO)](+) (salen = N,N'-bis-(salicylidene)ethyl-enediaminato); after photochemical NO photolabilization, SG-RuNO can be regenerated from the spent material via the subsequent reaction with aqueous nitrite.
引用
收藏
页码:4169 / 4171
页数:3
相关论文
共 31 条
[1]   Aqueous sol-gel process for protein encapsulation [J].
Bhatia, RB ;
Brinker, CJ ;
Gupta, AK ;
Singh, AK .
CHEMISTRY OF MATERIALS, 2000, 12 (08) :2434-2441
[2]   Nitric oxide photorelease from ruthenium salen complexes in aqueous and organic solutions [J].
Bordini, J ;
Hughes, DL ;
Neto, JDD ;
da Cunha, CJ .
INORGANIC CHEMISTRY, 2002, 41 (21) :5410-5416
[3]   Photochemistry of Roussin's red salt, Na-2[Fe2S2(NO)4], and of Roussin's black salt, NH4[Fe4S3(NO)7]. In situ nitric oxide generation to sensitize gamma-radiation induced cell death [J].
Bourassa, J ;
DeGraff, W ;
Kudo, S ;
Wink, DA ;
Mitchell, JB ;
Ford, PC .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (12) :2853-2860
[4]   [Ru-2(II)(ttha)(H2O)(2)](2-) is a rapid NO scavenger (ttha(6-) = triethylenetetraminehexaacetate) [J].
Chen, Y ;
Shepherd, RE .
JOURNAL OF INORGANIC BIOCHEMISTRY, 1997, 68 (03) :183-193
[5]   Sol-gels and electrochemistry: Research at the intersection [J].
Collinson, MM ;
Howells, AR .
ANALYTICAL CHEMISTRY, 2000, 72 (21) :702A-709A
[6]   Nitrite reduction to nitric oxide by deoxyhemoglobin vasodilates the human circulation [J].
Cosby, K ;
Partovi, KS ;
Crawford, JH ;
Patel, RP ;
Reiter, CD ;
Martyr, S ;
Yang, BK ;
Waclawiw, MA ;
Zalos, G ;
Xu, XL ;
Huang, KT ;
Shields, H ;
Kim-Shapiro, DB ;
Schechter, AN ;
Cannon, RO ;
Gladwin, MT .
NATURE MEDICINE, 2003, 9 (12) :1498-1505
[7]   A new inorganic vasodilator, trans-[Ru(NO)(NH3)4(POEt)3](PF6)3:: hypotensive effect of endothelium-dependent and -independent vasodilators in different hypertensive animals models [J].
de Barros, BF ;
Toledo, JC ;
Franco, DW ;
Tfouni, E ;
Krieger, MH .
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2002, 7 (01) :50-56
[8]   Emerging role of nitrite in human biology [J].
Dejam, A ;
Hunter, CJ ;
Schechter, AN ;
Gladwin, MT .
BLOOD CELLS MOLECULES AND DISEASES, 2004, 32 (03) :423-429
[9]  
Fang F.C., 1999, Nitric Oxide and Infection
[10]   Photochemistry of metal nitrosyl complexes. Delivery of nitric oxide to biological targets [J].
Ford, PC ;
Bourassa, J ;
Miranda, K ;
Lee, B ;
Lorkovic, I ;
Boggs, S ;
Kudo, S ;
Laverman, L .
COORDINATION CHEMISTRY REVIEWS, 1998, 171 :185-202