SiO2@Fe2O3 core-shell nanoparticles for covalent immobilization and release of sparfloxacin drug

被引：40

作者：

El-Gamel, Nadia E. A. ^{[2
]}

Wortmann, Laura ^{[1
]}

Arroub, Karim ^{[1
]}

Mathur, Sanjay ^{[1
]}

机构：

[1] Univ Cologne, Inst Inorgan Chem, D-50939 Cologne, Germany

[2] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 36期

关键词：

TEMPLATE-FREE SYNTHESIS; PARTICLES; HYDROLYSIS; NANORODS; SPHERES;

D O I：

10.1039/c1cc13708e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Silica-coated Fe2O3 nanoparticles were synthesized as carriers for the covalent immobilization and release of antimicrobial drug sparfloxacin (SPFX). SPFX-loaded nanoparticles exhibited time-dependent drug release, with no measurable in vitro cytotoxicity, making the drug@nanoparticle conjugates potentially relevant for nanomedicine applications.

引用

页码：10076 / 10078

页数：3

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