Thinking Clearly About Schizotypy: Hewing to the Schizophrenia Liability Core, Considering Interesting Tangents, and Avoiding Conceptual Quicksand

被引:80
作者
Lenzenweger, Mark F. [1 ,2 ]
机构
[1] SUNY Binghamton, Dept Psychol, Binghamton, NY 13902 USA
[2] Weill Cornell Med Coll, Dept Psychiat, New York, NY USA
关键词
schizotypy; schizophrenia; endophenotype; liability; latent structure; schizotype; LATENT STRUCTURE; PSYCHOPATHOLOGY;
D O I
10.1093/schbul/sbu184
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
The concept of schizotypy represents a rich and complex psychopathology construct. Furthermore, the construct implies a theoretical model that has considerable utility as an organizing framework for the study of schizophrenia, schizophrenia-related psychopathology (eg, delusional disorder, psychosis-NOS (not otherwise specified), schizotypal, and paranoid personality disorder), and putative schizophrenia endophenotypes as suggested by Rado, Meehl, Gottesman, Lenzenweger, and others. The understanding (and misunderstanding) of the schizophrenia-related schizotypy model, particularly as regards clinical illness, as well as an alternative approach to the construct require vigilance in order to ensure the methodological approach continues to yield the fruit that it can in illuminating the pathogenesis of schizophrenia-related psychopathology. The articles in the Special Section in this issue of Schizophrenia Bulletin highlight methodological and theoretical issues that should be examined carefully.
引用
收藏
页码:S483 / S491
页数:9
相关论文
共 25 条
[1]  
Arnedo J, 2014, AM J PSYCHI IN PRESS
[2]  
Bleuler E., 1911, Dementia Praecox or the group of schizophrenias
[3]  
Claridge G., 1997, SCHIZOTYPY IMPLICATI
[4]   The Psychosis High-Risk State A Comprehensive State-of-the-Art Review [J].
Fusar-Poli, Paolo ;
Borgwardt, Stefan ;
Bechdolf, Andreas ;
Addington, Jean ;
Riecher-Rossler, Anita ;
Schultze-Lutter, Frauke ;
Keshavan, Matcheri ;
Wood, Stephen ;
Ruhrmann, Stephan ;
Seidman, Larry J. ;
Valmaggia, Lucia ;
Cannon, Tyrone ;
Velthorst, Eva ;
De Haan, Lieuwe ;
Cornblatt, Barbara ;
Bonoldi, Ilaria ;
Birchwood, Max ;
McGlashan, Thomas ;
Carpenter, William ;
McGorry, Patrick ;
Klosterkotter, Joachim ;
McGuire, Philip ;
Yung, Alison .
JAMA PSYCHIATRY, 2013, 70 (01) :107-120
[5]  
Gottesman I.I., 1991, Schizophrenia genesis: the origins of madness
[6]   The endophenotype concept in psychiatry: Etymology and strategic intentions [J].
Gottesman, II ;
Gould, TD .
AMERICAN JOURNAL OF PSYCHIATRY, 2003, 160 (04) :636-645
[7]  
Kraepelin E., 1909, Dementia praecox and paraphrenia
[8]   Initial construction of a maladaptive personality trait model and inventory for DSM-5 [J].
Krueger, R. F. ;
Derringer, J. ;
Markon, K. E. ;
Watson, D. ;
Skodol, A. E. .
PSYCHOLOGICAL MEDICINE, 2012, 42 (09) :1879-1890
[9]  
Lenzenweger M. F., 2015, OXFORD TXB PSYCHOPAT, P729
[10]  
Lenzenweger M.F., 2010, SCHIZOTYPY SCHIZOPHR