Synthesis of Vinyl Boronates from Aldehydes by a Practical Boron-Wittig Reaction

被引：176

作者：

Coombs, John R. ^{[1
]}

Zhang, Liang ^{[1
]}

Morken, James P. ^{[1
]}

机构：

[1] Boston Coll, Dept Chem, Merkert Chem Ctr, Chestnut Hill, MA 02467 USA

来源：

ORGANIC LETTERS | 2015年 / 17卷 / 07期

基金：

美国国家卫生研究院;

关键词：

OLEFIN CROSS-METATHESIS; CATALYZED ASYMMETRIC 1,4-ADDITION; TERMINAL ALKYNES; STEREOSELECTIVE-SYNTHESIS; HYDROBORATION REAGENT; CONVENIENT SYNTHESIS; CARBONYL-COMPOUNDS; COUPLING REACTIONS; INTERNAL ALKYNES; HIGHLY REGIO;

D O I：

10.1021/acs.orglett.5b00480

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly stereoselective boron-Wittig reaction between stable and readily accessible 1,1-bis(pinacolboronates) and aldehydes furnishes a variety of synthetically useful di- and trisubstituted vinyl boronate esters.

引用

页码：1708 / 1711

页数：4

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