Parathyroid hormone-related protein-induced hypercalcemia due to osteosarcoma in a cat

被引：4
作者：
Yuki, Masashi [1 ]
Nitta, Makiko [1 ]
Omachi, Tetsuo [2 ]
机构：
[1] Yuki Anim Hosp, Nagoya, Aichi, Japan
[2] Patho Labo Co Ltd, Shizuoka, Kanagawa, Japan
来源：
VETERINARY CLINICAL PATHOLOGY | 2015年 / 44卷 / 01期
关键词：
Endocrine; feline; HHM; malignant mesenchymal tumor; paraneoplastic syndrome; HUMORAL HYPERCALCEMIA; MALIGNANCY;
D O I：
10.1111/vcp.12224
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
A 15-year-old castrated male mixed-breed cat was presented with a history of sarcoma of the distal right hind limb. Biochemical analysis revealed increased concentrations of blood urea, creatinine, total calcium, ionized calcium, and parathyroid hormone-related protein (PTHrP). The mass was removed surgically by amputation of the hind limb. Osteosarcoma was diagnosed based on histopathologic examination. All abnormal serum analyte concentrations improved immediately after surgery, including azotemia, total calcium, ionized calcium, and PTHrP. The biochemical results were attributed to osteosarcoma causing PTHrP-induced hypercalcemia.
引用
收藏
页码：141 / 144
页数：4
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