Radioactivity characterization of 125I brachytherapy seeds used in prostate cancer treatment

被引：2

作者：

Ruzzarin, Anelise ^{[1
]}

Lima da Cruz, Paulo Alberto ^{[2
]}

de Almeida Rangel, Johnny ^{[2
]}

da Silva, Carlos Jose ^{[2
]}

Iwahara, Akira ^{[2
]}

Lopes, Ricardo Tadeu ^{[1
]}

机构：

[1] Univ Fed Rio de Janeiro PEN COPPE UFRJ, Programa Engn Nucl, Coordenacao Programas Posgrad Engn, Caixa Postal 68509, BR-21945970 Rio De Janeiro, Brazil

[2] CNEN, IRD, LNMRI, Av Salvador Allende S, BR-22783127 Rio De Janeiro, Brazil

来源：

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY | 2020年 / 323卷 / 02期

关键词：

I-125; seeds; Brachytherapy; Sum-peak coincidence; Ionization chamber; NAI T1 CRYSTAL; ABSOLUTE STANDARDIZATION; DOSIMETRIC CHARACTERISTICS; CALIBRATION; DISSOLUTION;

D O I：

10.1007/s10967-019-06997-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A procedure for characterizing the activity amount of I-125 seed was developed in order to establish a secondary standard activity measurement system based on an IG11 ionization chamber. Initially the ion current generated by the seed in the ionization chamber is measured and then its activity determined in a destructive analysis. The analysis consists in complete dissolution of the seeds to obtain a homogeneous solution to enable the primary measurements based in the coincidence sum-peak measurements. The measured current and activity allows determining the calibration factor, in pA MBq(-1), for seed geometry. A detailed description of the procedure implemented for the seed dissolution is described.

引用

页码：721 / 729

页数：9

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