Synthesis of 5-amino-4-(4-aryl-2-thiazolyl)-2,3-dihydro-2-pyrrolones

被引：3
作者：
Resnyanskaya, EV [1 ]
Tverdokhlebov, AV
Tolmachev, AA
Volovenko, YM
机构：
[1] OOO NVP Enamin, UA-02042 Kiev, Ukraine
[2] Taras Shevchenko Kiev Natl Univ, Kiev, Ukraine
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 41卷 / 02期
关键词：
D O I：
10.1007/s11178-005-0153-7
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A method was developed for preparation of 5-amino-4-(4-aryl-2-thiazolyl)-2,3-dihydro-2-pyrrolones by alkylation of 4-aryl-2-thiazolylacetonitriles by N-substituted chloroacetamides in the presence of K2CO3. In 1-(1-naphthyl)-substituted pyrrolones atropoisomerism was observed.
引用
收藏
页码：257 / 260
页数：4
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