Type 2 Diabetes, Hypoglycemia, and Basal Insulins: Ongoing Challenges

被引：11
作者：
Blumer, Ian [1 ,2 ]
Clement, Maureen [3 ]
机构：
[1] Charles H Best Diabet Ctr, Ajax, ON, Canada
[2] Univ Toronto, Dept Med, Toronto, ON, Canada
[3] Univ British Columbia, Diabet Educ Ctr, Vernon, BC, Canada
来源：
CLINICAL THERAPEUTICS | 2017年 / 39卷 / 08期
关键词：
basal insulin; hypoglycemia; management; type; 2; diabetes; TO-TARGET TRIAL; PATIENT-REPORTED OUTCOMES; GLARGINE; 100; UNITS/ML; GLYCEMIC CONTROL; COGNITIVE FUNCTION; GLUCOSE CONTROL; NPH INSULIN; PEOPLE; DEGLUDEC; RISK;
D O I：
10.1016/j.clinthera.2016.09.020
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Hypoglycemia in people with insulin-treated type 2 diabetes can be a limiting factor for management and a barrier to optimizing glycemic control. Even mild episodes of hypoglycemia can affect an individual's quality of life, and fear of hypoglycemia can lead to underinsulinization. This article explores the prevalence and consequences of hypoglycemia in people with type 2 diabetes with a focus on those who use basal insulins, offering strategies for prevention and management. It also discusses the benefits and challenges associated with new basal insulins, and their potential role in reducing hypoglycemia risk. (C) 2017 Elsevier HS Journals, Inc. All rights reserved.
引用
收藏
页码：S1 / S11
页数：11
相关论文
共 50 条
  • [1] Switching basal insulins in type 2 diabetes: practical recommendations for health care providers
    Anderson, Sarah L.
    Trujillo, Jennifer M.
    Anderson, John E.
    Tanenberg, Robert J.
    POSTGRADUATE MEDICINE, 2018, 130 (02) : 229 - 238
  • [2] Clinical Outcomes of Switching to Insulin Glargine 300 U/ml from Other Basal Insulins in People with Type 2 Diabetes in Italy: A Real-World Study
    Ragonese, Mauro
    Larosa, Monica
    Angotti, Stefania
    Annese, Stefania
    Cruciani, Laura
    Dainelli, Michela
    Lucisano, Giuseppe
    Prosperini, Giuseppe
    Sacco, Michele
    Salomone, Enrica
    Saponara, Caterina
    Semprini, Roberta
    Rossi, Maria Chiara
    Nicolucci, Antonio
    DIABETES THERAPY, 2020, 11 (10) : 2283 - 2298
  • [3] The role of basal insulins in the treatment of people with type 2 diabetes and chronic kidney disease: A narrative review
    Sloan, Lance
    Cheng, Alice Y. Y.
    Escalada, Javier
    Haluzik, Martin
    Mauricio, Didac
    DIABETES OBESITY & METABOLISM, 2024, 26 (04) : 1157 - 1170
  • [4] New Basal Insulins: a Clinical Perspective of Their Use in the Treatment of Type 2 Diabetes and Novel Treatment Options Beyond Basal Insulin
    Frias, Patrick F.
    Frias, Juan Pablo
    CURRENT DIABETES REPORTS, 2017, 17 (10)
  • [5] New Injectable Agents for the Treatment of Type 2 Diabetes Part 1-Injectable Insulins
    George, Christa M.
    Byun, AhYoung
    Howard-Thompson, Amanda
    AMERICAN JOURNAL OF MEDICINE, 2018, 131 (07) : 752 - 754
  • [6] Using 2nd generation basal insulins in type 2 diabetes: Costs and savings in a comparative economic analysis in Italy, based on the BRIGHT study
    Napoli, Raffaele
    Fanelli, Francesca
    Gazzi, Luca
    Larosa, Monica
    Bitonti, Rossella
    Furneri, Gianluca
    NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2020, 30 (11) : 1937 - 1944
  • [7] The Diabetes Unmet Need with Basal Insulin Evaluation (DUNE) study in type 2 diabetes: Achieving HbA1c targets with basal insulin in a real-world setting
    Meneghini, Luigi F.
    Mauricio, Didac
    Orsi, Emanuela
    Lalic, Nebojsa M.
    Cali, Anna M. G.
    Westerbacka, Jukka
    Stella, Peter
    Candelas, Christophe
    Pilorget, Valerie
    Perfetti, Riccardo
    Khunti, Kamlesh
    DIABETES OBESITY & METABOLISM, 2019, 21 (06) : 1429 - 1436
  • [8] Observational Registry of Basal Insulin Treatment in Patients with Type 2 Diabetes in China: Safety and Hypoglycemia Predictors
    Zhang, Tingting
    Ji, Linong
    Gao, Yan
    Zhang, Puhong
    Zhu, Dongshan
    Li, Xian
    Ji, Jiachao
    Zhao, Fang
    Zhang, Heng
    Guo, Xiaohui
    DIABETES TECHNOLOGY & THERAPEUTICS, 2017, 19 (11) : 675 - 684
  • [9] Persistence with Basal Insulin and Frequency of Hypoglycemia Requiring Hospitalization in Patients with Type 2 Diabetes
    Roussel, Ronan
    Detournay, Bruno
    Boultif, Zahra
    Bahloul, Amar
    Teissier, Clement
    Charbonnel, Bernard
    DIABETES THERAPY, 2020, 11 (08) : 1861 - 1872
  • [10] Update on Basal Insulin Therapy for Type 2 Diabetes Mellitus
    Patel, Hansita B.
    Witte, Amy P.
    US PHARMACIST, 2021, 46 (11) : 44 - 50
12345