Ageing of the Diaphragm Muscle

被引:27
作者
Bordoni, Bruno [1 ]
Morabito, Bruno [2 ]
Simonelli, Marta [3 ]
机构
[1] Fdn Don Carlo Gnocchi, Phys Med & Rehabil, Milan, Italy
[2] Ctr Res & Studies, Phys Med & Rehabil, Sch Osteopath, Milan, Italy
[3] French Italian Sch Osteopathy, Integrat Complimentary Med, Pisa, Italy
关键词
diaphragm; ageing; fascia; skeletal muscle; phrenic nerve; vagus nerve; sarcopenia; DEPRESSION; DISEASE; INFLAMMATION; POPULATION; SARCOPENIA; EXERCISE; ANXIETY; REFLEX; HEALTH; ADULTS;
D O I
10.7759/cureus.6645
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The diaphragm muscle is the most important contractile district used for breathing. Like other muscles in the human body, it is subject to ageing and sarcopenia. Sarcopenia can be classified as primary (or age-related) when there are no local or systemic pathologies that cause a functional and morphological detriment of skeletal musculature. Secondary sarcopenia occurs when there is a cause or more pathological causes (illness, malnutrition, immobility) related or unrelated to ageing. In the elderly population, transdiaphragmatic pressure (Pdi) decreases by 20-41%, with a decline in the overall strength of 30% (the strength of the expiratory muscles also decreases). The article discusses the adaptation of the diaphragm muscle to ageing and some other ailments and co-morbidities, such as back pain, emotional alterations, motor incoordination, and cognitive disorders, which are related to breathing.
引用
收藏
页数:10
相关论文
共 49 条
[21]   Epidemiology, progression, and predictive factors of urinary incontinence in older community-dwelling Mexican adults: Longitudinal data from the Mexican Health and Aging Study [J].
Giraldo-Rodriguez, Liliana ;
Agudelo-Botero, Marcela ;
Mino-Leon, Dolores ;
Alvarez-Cisneros, Teresa .
NEUROUROLOGY AND URODYNAMICS, 2019, 38 (07) :1932-1943
[22]   Diaphragm plasticity in aging and disease: therapies for muscle weakness go from strength to strength [J].
Greising, Sarah M. ;
Ottenheijm, Coen A. C. ;
O'Halloran, Ken D. ;
Barreiro, Esther .
JOURNAL OF APPLIED PHYSIOLOGY, 2018, 125 (02) :243-253
[23]   Regulation of skeletal muscle blood flow during exercise in ageing humans [J].
Hearon, Christopher M., Jr. ;
Dinenno, Frank A. .
JOURNAL OF PHYSIOLOGY-LONDON, 2016, 594 (08) :2261-2273
[24]   Intra-abdominal pressure increases stiffness of the lumbar spine [J].
Hodges, PW ;
Eriksson, AEM ;
Shirley, B ;
Gandevia, SC .
JOURNAL OF BIOMECHANICS, 2005, 38 (09) :1873-1880
[25]   Physical performance reflects cognitive function, fall risk, and quality of life in community-dwelling older people [J].
Ikegami, Shota ;
Takahashi, Jun ;
Uehara, Masashi ;
Tokida, Ryosuke ;
Nishimura, Hikaru ;
Sakai, Ayaka ;
Kato, Hiroyuki .
SCIENTIFIC REPORTS, 2019, 9 (1)
[26]   Load dependence of secondary diaphragm inflammation and injury after acute inspiratory loading [J].
Jiang, TX ;
Reid, WD ;
Belcastro, A ;
Road, JD .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 157 (01) :230-236
[27]   Age-related and disease-related muscle loss: the effect of diabetes, obesity, and other diseases [J].
Kalyani, Rita Rastogi ;
Corriere, Mark ;
Ferrucci, Luigi .
LANCET DIABETES & ENDOCRINOLOGY, 2014, 2 (10) :819-829
[28]   Advanced aging causes diaphragm functional abnormalities, global proteome remodeling, and loss of mitochondrial cysteine redox flexibility in mice [J].
Kelley, Rachel C. ;
McDonagh, Brian ;
Ferreira, Leonardo F. .
EXPERIMENTAL GERONTOLOGY, 2018, 103 :69-79
[29]   Gender, mental health and ageing [J].
Kiely, Kim M. ;
Brady, Brooke ;
Byles, Julie .
MATURITAS, 2019, 129 :76-84
[30]   Impact of diaphragm function parameters on balance maintenance [J].
Kocjan, Janusz ;
Gzik-Zroska, Bozena ;
Nowakowska, Katarzyna ;
Burkacki, Michal ;
Suchon, Slawomir ;
Michnik, Robert ;
Czyzewski, Damian ;
Adamek, Mariusz .
PLOS ONE, 2018, 13 (12)