Psychiatric Symptoms Associated with Focal Hand Dystonia

被引：34

作者：

Voon, Valerie ^{[1
,2
]}

Butler, Tracy R. ^{[1
]}

Ekanayake, Vindhya ^{[1
]}

Gallea, Cecile ^{[1
]}

Ameli, Rezvan ^{[3
]}

Murphy, Dennis L. ^{[3
]}

Hallett, Mark ^{[1
]}

机构：

[1] Natl Inst Neurol Disorders & Stroke, NIH, Bethesda, MD USA

[2] Univ Cambridge, Behav & Clin Neurosci Inst, Cambridge, England

[3] NIMH, NIH, Bethesda, MD 20892 USA

来源：

MOVEMENT DISORDERS | 2010年 / 25卷 / 13期

基金：

美国国家卫生研究院;

关键词：

obsessive compulsive disorder; depression; dystonia; striatum; obsession; compulsion; OBSESSIVE-COMPULSIVE DISORDER; MYOCLONUS-DYSTONIA; PUTAMEN;

D O I：

10.1002/mds.23250

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Myoclonus dystonia and idiopathic dystonia are associated with a greater frequency of obsessive compulsive disorder (OCD) and major depression. We investigated the frequency of OCD in 39 patients with primary focal hand dystonia (FHD) using a semistructured interview. OCD and subsyndromal OCD was diagnosed in 5 of 39 (12.82%) patients with FHD, whereas OCD occurs in 2.3% of the general population. Recurrent depression occurred in (7 of 39) 17.95% of patients with FHD along with a family history of depression in (16 of 39) 41.02%. Overlapping mechanisms manifesting as FHD may also predispose to OC symptoms and likely implicates a common striatal dysfunction. (C) 2010 Movement Disorder Society

引用

页码：2249 / 2252

页数：4

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