Diorgano, dichloro-tin (IV) complexes of 4-X-benzohydroxamic acid (X=Cl, OCH3):: Synthesis, characterization, antitumor activity in vitro and the crystal structure of trans- [Me2Sn (L2)2]

被引:0
|
作者
Zhao, JH
Liang, TG
Li, QS [1 ]
Pombeiro, AJL
机构
[1] Shanxi Med Univ, Sch Pharmaceut Sci, Taiyuan 030001, Peoples R China
[2] Inst Super Tecn, P-1049001 Lisbon, Portugal
关键词
diorganotin; X-ray diffraction; antitumor activity; synthesis;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A series of diorganotin (IV) derivatives of R2SnL2 (R = Me, Et, n-Bu, ph or Cl; L = L, or L-2) and their corresponding mixed-ligand complexes R2Sn (L,)(L2) have been prepared and the structure of trans-Me2Sn (L-2)(2) was characterized by FT-IR, H-1, C-13 and Sn-119 NMR spectroscopies, MS, elemental analysis, melting points and X-ray diffraction. The structure-activity relationships were discussed.
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页码:840 / 843
页数:4
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