Some early biochemical changes in rat brain after single exposure to anaesthetic ether

被引：0
作者：
Viswanathan, V
Kakkar, P
Seth, PK
机构：
来源：
JOURNAL OF ENVIRONMENTAL BIOLOGY | 1996年 / 17卷 / 01期
关键词：
anaesthetic ether; neurotoxicity; free radicals; lipid peroxidation; antioxidants; RNA;
D O I：
暂无
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
A single sublethal, short term exposure to anaesthetic ether, caused leakage of proteins from mitochondria, without any. major change in cytosolic lactic dehydrogenase and mitochondrial cytochrome oxidase activity. A higher rate of lipid peroxidation in the treated rats indicated damage to biomembranes. A significant increase in cytosolic Ou-Zn superoxide dismutase immediately after the ether exposure was also observed. The initial rate of incorporation of radioactive glycine into RNA was two fold higher on ether exposure, suggesting a possible higher m-RNA turnover.
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页码：1 / 4
页数：4
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