Low-field portable brain MRI in CNS demyelinating disease

被引：15

作者：

Mateen, Farrah J. ^{[1
]}

Cooley, Clarissa Zimmerman ^{[2
,3
]}

Stockmann, Jason P. ^{[2
,3
]}

Rice, Dylan R. ^{[1
]}

Vogel, Andre C. ^{[1
]}

Wald, Lawrence L. ^{[2
,3
,4
]}

机构：

[1] Massachusetts Gen Hosp, Dept Neurol, 165 Cambridge St,627, Boston, MA 02114 USA

[2] Massachusetts Gen Hosp, Dept Radiol, 32 Fruit St, Boston, MA 02114 USA

[3] Massachusetts Gen Hosp, Athinoula A Martinos Ctr Biomed Imaging, Boston, MA 02114 USA

[4] Harvard MIT Div Hlth Sci & Technol, Cambridge, MA USA

来源：

MULTIPLE SCLEROSIS AND RELATED DISORDERS | 2021年 / 51卷

关键词：

Neuroimaging; Magnetic resonance imaging; Demyelinating disease; Multiple sclerosis;

D O I：

10.1016/j.msard.2021.102903

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A low-field (80 mT), portable MRI scanner has been developed that may address barriers to MRI for people with multiple sclerosis (MS). As a proof of concept study, we imaged two participants with central nervous system demyelinating disease by both a standard 1.5 Tesla MRI and the portable MRI scanner. These images demonstrate the ability to identify a solitary demyelinating lesion in early stage disease and cortical atrophy and chronic white matter changes in late stage disease. In spite of device limitations, including border distortion and lower image quality, the portable device has important implications for addressing barriers to care in people with MS.

引用

页数：2

共 4 条

[1] A portable scanner for magnetic resonance imaging of the brain [J].

Cooley, Clarissa Z. ;

McDaniel, Patrick C. ;

Stockmann, Jason P. ;

Srinivas, Sai Abitha ;

Cauley, Stephen F. ;

Sliwiak, Monika ;

Sappo, Charlotte R. ;

Vaughn, Christopher F. ;

Guerin, Bastien ;

Rosen, Matthew S. ;

Lev, Michael H. ;

Wald, Lawrence L. .

NATURE BIOMEDICAL ENGINEERING, 2021, 5 (03) :229-239

[2] Accessible magnetic resonance imaging: A review [J].

Geethanath, Sairam ;

Vaughan, John Thomas, Jr. .

JOURNAL OF MAGNETIC RESONANCE IMAGING, 2019, 49 (07) :E65-E77

[3] Availability, accessibility, and affordability of neurodiagnostic tests in 37 countries [J].

McLane, Hannah C. ;

Berkowitz, Aaron L. ;

Patenaude, Bryan N. ;

McKenzie, Erica D. ;

Wolper, Emma ;

Wahlster, Sarah ;

Fink, Guenther ;

Mateen, Farrah J. .

NEUROLOGY, 2015, 85 (18) :1614-1622

[4] Low-cost and portable MRI [J].

Wald, Lawrence L. ;

McDaniel, Patrick C. ;

Witzel, Thomas ;

Stockmann, Jason P. ;

Cooley, Clarissa Zimmerman .

JOURNAL OF MAGNETIC RESONANCE IMAGING, 2020, 52 (03) :686-696

← 1 →