Yeast Biosensors for Detection of Environmental Pollutants: Current State and Limitations

被引:61
作者
Jarque, Sergio [1 ]
Bittner, Michal [1 ]
Blaha, Ludek [1 ]
Hilscherova, Klara [1 ]
机构
[1] Masaryk Univ, Fac Sci, RECETOX, Kamenice 5, Brno 62500, Czech Republic
关键词
IN-VITRO ASSESSMENT; WASTE-WATER; ESTROGEN SCREEN; ACTIVE-CHEMICALS; RECEPTOR LIGANDS; REPORTER ASSAY; COPPER IONS; CELLS; SYSTEM; BIOASSAY;
D O I
10.1016/j.tibtech.2016.01.007
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Yeast biosensors have become suitable tools for the screening and detection of environmental pollutants because of their various advantages compared to other sensing technologies. On the other hand, many limitations remain with regard to their optimal performance and applicability in several contexts, such as low-concentration samples and on-site testing. This review summarizes the current state of yeast biosensors, with special focus on screening and assessment of environmental contaminants, discusses both pros and cons, and suggests steps towards their further development and effective use in the environmental assessment.
引用
收藏
页码:408 / 419
页数:12
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