Salivary gland dysfunction after radioactive iodine (I-131) therapy in patients following total thyroidectomy: emphasis on radioactive iodine therapy dose

被引：32

作者：

Lee, Han Na ^{[1
]}

An, Ji Young ^{[1
]}

Lee, Kyung Mi ^{[1
]}

Kim, Eui Jong ^{[1
]}

Choi, Woo Suk ^{[1
]}

Kim, Deog Yoon ^{[2
]}

机构：

[1] Kyung Hee Univ, Coll Med, Dept Radiol, Seoul 130872, South Korea

[2] Kyung Hee Univ, Coll Med, Dept Nucl Med, Seoul 130872, South Korea

来源：

CLINICAL IMAGING | 2015年 / 39卷 / 03期

关键词：

Salivary gland dysfunction; Radioiodine therapy; Total thyroidectomy; Radiation sialadenitis; RADIOIODINE THERAPY; CANCER; CARCINOMA; ABLATION;

D O I：

10.1016/j.clinimag.2014.12.018

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Purpose: The purpose of this study was to retrospectively evaluate symptoms, images of salivary gland dysfunction, and related clinical factors in thyroid cancer patients with total thyroidectomy followed by radioiodine therapy (RIT). Methods: We included 164 patients who underwent thyroid ultrasonography or contrast-enhanced neck computed tomography more than 6 months later after RIT. Correlation between subjective symptoms and various Rh doses was also evaluated. Results: Swelling and decreased salivary volume were the most common symptoms and images. RIT dose was the only factor with a positive correlation (P<.001). Conclusion: The dose of RIT should be carefully determined to minimize gland dysfunction. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：396 / 400

页数：5

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