Histological and dimensional changes of the alveolar ridge following tooth extraction when using collagen matrix and collagen-embedded xenogenic bone substitute: A randomized clinical trial

被引:14
作者
Gabay, Eran [1 ,2 ]
Katorza, Anat [1 ]
Zigdon-Giladi, Hdar [1 ,2 ]
Horwitz, Jacob [1 ,2 ]
Machtei, Eli E. [1 ,2 ]
机构
[1] Rambam Hlth Care Campus, Dept Periodontol & Implant Dent, Haaliya Hashniya 8, IL-3109601 Haifa, Israel
[2] Technion Israel Inst Technol, Rappaport Fac Med, Haifa, Israel
关键词
alveolar ridge dimensions; alveolar ridge preservation; collagen embedded xenogenic bone substitute; core biopsy; non-molars area; FREEZE-DRIED BONE; SOCKET PRESERVATION; BUCCAL WALL; OUTCOMES;
D O I
10.1111/cid.13085
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Aim To assess the horizontal and vertical dimensional changes of the alveolar ridge when using a collagen matrix in combination with collagen embedded xenogenic bone substitute, in comparison with natural healing after tooth extraction. Methods Patients that required extraction in non-molars areas were included. Test group-15 sockets were treated with deproteinized bovine bone mineral containing 10% collagen (DBBM-C), covered by a procaine collagen membrane (CMXs). Control group-15 sockets left for spontaneous healing. We used a custom-made acrylic stent as a reference for alveolar ridge measurements. Six-month postoperative, a single implant was placed in the experimental site. A core biopsy was taken from the site, using a trephine bur. Histomorphometric analysis assessed bone area, connective tissue, bone marrow, and residual bone graft. Results Six months later, horizontal ridge width at -3 mm showed a significant (p < 0.05) reduction in both groups albeit smaller in the test group 1.19 +/- 1.55 mm, compared with the control 2.27 +/- 1.52 (p = 0.087). At -5 mm sub-crestally, statistically non-significant reduction was noted in both groups, 1.61 +/- 1.53 and 1.96 +/- 1.52 mm for the test and control groups, respectively (p = 0.542). Vertical changes were smaller in the test group (0.14 +/- 1.84 mm) compared with control (0.98 +/- 1.49 mm). Keratinized tissue (KT) width was 7.3 +/- 2.13 and 7.5 +/- 3.49 mm in the test and control groups, respectively. Newly formed bone occupied 33.79 +/- 17.37% and 51.14 +/- 23.04% in the test and control groups, respectively, (p = 0.11). Connective tissue volume was 33.74 +/- 13.81% and 30.12 +/- 18.32% in the test and control groups, respectively (p = 0.65). Bone marrow occupied 19.57 +/- 10.26% and 18.74 +/- 17.15% in the test and control groups, respectively (p = 0.91). Residual graft occupied 12.9 +/- 9.88% in the test group. Conclusion Alveolar ridge preservation using DBBM-C resulted in reductions of the vertical and horizontal dimensions albeit not reaching statistical significance. The larger than anticipated standard deviation and smaller inter-group differences might account for this phenomenon.
引用
收藏
页码:382 / 390
页数:9
相关论文
共 35 条
  • [1] Ackermann KL, 2009, INT J PERIODONT REST, V29, P489
  • [2] Three-dimensional analysis of bone remodeling following ridge augmentation of compromised extraction sockets in periodontitis patients: A randomized controlled study
    Aimetti, Mario
    Manavella, Valeria
    Corano, Lisa
    Ercoli, Elena
    Bignardi, Cristina
    Romano, Federica
    [J]. CLINICAL ORAL IMPLANTS RESEARCH, 2018, 29 (02) : 202 - 214
  • [3] Histological comparison of healing following tooth extraction with ridge preservation using enamel matrix derivatives versus Bio-Oss Collagen: a pilot study
    Alkan, E. A.
    Parlar, A.
    Yildirim, B.
    Senguven, B.
    [J]. INTERNATIONAL JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2013, 42 (12) : 1522 - 1528
  • [4] Ridge preservation with the use of Bio-Oss® collagen: A 6-month study in the dog
    Araujo, Mauricio G.
    Lindhe, Jan
    [J]. CLINICAL ORAL IMPLANTS RESEARCH, 2009, 20 (05) : 433 - 440
  • [5] Porous bovine bone mineral in healing of human extraction sockets: 2. Histochemical observations at 9 months
    Artzi, Z
    Tal, H
    Dayan, D
    [J]. JOURNAL OF PERIODONTOLOGY, 2001, 72 (02) : 152 - 159
  • [6] Interventions for replacing missing teeth: alveolar ridge preservation techniques for dental implant site development
    Atieh, M. A.
    Alsabeeha, N. H. M.
    Payne, A. G. T.
    Ali, S.
    Faggion, C. M. J.
    Esposito, M.
    [J]. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2021, (04):
  • [7] Effect of alveolar ridge preservation interventions following tooth extraction: A systematic review and meta-analysis
    Avila-Ortiz, Gustavo
    Chambrone, Leandro
    Vignoletti, Fabio
    [J]. JOURNAL OF CLINICAL PERIODONTOLOGY, 2019, 46 : 195 - 223
  • [8] Is ridge preservation effective in the extraction sockets of periodontally compromised teeth? A randomized controlled trial
    Ben Amara, Heithem
    Kim, Jung-Ju
    Kim, Hae-Young
    Lee, Jungwon
    Song, Hyun-Young
    Koo, Ki-Tae
    [J]. JOURNAL OF CLINICAL PERIODONTOLOGY, 2021, 48 (03) : 464 - 477
  • [9] Alveolar ridge dimensional changes after two socket sealing techniques. A pilot randomized clinical trial
    Debel, M.
    Toma, S.
    Vandenberghe, B.
    Brecx, M. C.
    Lasserre, J. F.
    [J]. CLINICAL ORAL INVESTIGATIONS, 2021, 25 (03) : 1235 - 1243
  • [10] Felice P, 2011, EUR J ORAL IMPLANTOL, V4, P329