Palladium-Catalyzed Direct Hydroxymethylation of Aryl Halides and Inflates with Potassium Acetoxymethyltrifluoroborate

被引：34
作者：
Murai, Norio [1 ,2 ]
Yonaga, Masahiro [1 ,2 ]
Tanaka, Keigo [2 ]
机构：
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan
[2] Eisai & Co Ltd, Discovery Res Labs, Tsukuba, Ibaraki 3002635, Japan
来源：
ORGANIC LETTERS | 2012年 / 14卷 / 05期
关键词：
CROSS-COUPLING REACTIONS; ORGANIC-SYNTHESIS; DERIVATIVES; INHIBITORS; CHLORIDES;
D O I：
10.1021/ol300149b
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Suzuki-Miyaura cross-coupling reactions of aryl halides and triflates with potassium acetoxymethyltrifluoroborate afforded the corresponding aryl and heteroaryl methanol products in moderate to excellent yields.
引用
收藏
页码：1278 / 1281
页数：4
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