共 50 条
Palladium-Catalyzed Direct Hydroxymethylation of Aryl Halides and Inflates with Potassium Acetoxymethyltrifluoroborate
被引:34
|作者:
Murai, Norio
[1
,2
]
Yonaga, Masahiro
[1
,2
]
Tanaka, Keigo
[2
]
机构:
[1] Univ Tokyo, Grad Sch Pharmaceut Sci, Bunkyo Ku, Tokyo 1130033, Japan
[2] Eisai & Co Ltd, Discovery Res Labs, Tsukuba, Ibaraki 3002635, Japan
关键词:
CROSS-COUPLING REACTIONS;
ORGANIC-SYNTHESIS;
DERIVATIVES;
INHIBITORS;
CHLORIDES;
D O I:
10.1021/ol300149b
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
Suzuki-Miyaura cross-coupling reactions of aryl halides and triflates with potassium acetoxymethyltrifluoroborate afforded the corresponding aryl and heteroaryl methanol products in moderate to excellent yields.
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页码:1278 / 1281
页数:4
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