Mechanisms of lipid body formation

被引：499
作者：
Murphy, DJ
Vance, J
机构：
[1] John Innes Ctr Plant Sci Res, Dept Brassica & Oilseeds Res, Norwich NR4 7UH, Norfolk, England
[2] Univ Alberta, Lipid & Lipoprot Res Grp, Edmonton, AB T6G 2S2, Canada
[3] Univ Alberta, Dept Med, Edmonton, AB T6G 2S2, Canada
来源：
TRENDS IN BIOCHEMICAL SCIENCES | 1999年 / 24卷 / 03期
基金：
英国生物技术与生命科学研究理事会;
关键词：
D O I：
10.1016/S0968-0004(98)01349-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Most organisms transport or store neutral lipids as lipid bodies - lipid droplets that usually are bounded by specific proteins and (phospho)lipid, Neutral-lipid bodies vary considerably in their morphology and are associated with an extremely diverse range of proteins. However, the mechanisms by which they are generated in plants, animals and microorganisms appear to share many common features: lipid bodies probably arise from microdomains of the endoplasmic reticulum (or the plasma membrane in prokaryotes) that contain lipid-biosynthesis enzymes, and their synthesis and size appear to be controlled by specific protein components.
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收藏
页码：109 / 115
页数：7
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