A concise synthesis of (+)-botryolide-E and its C-7 epimer

被引：9

作者：

Liu, Xiaojing ^{[1
]}

Chen, Ruijiao ^{[1
,2
]}

Duan, Feixia ^{[3
]}

Jia, Junhao ^{[1
]}

Zhou, Yuqin ^{[1
]}

Chen, Xiaochuan ^{[1
]}

机构：

[1] Sichuan Univ, Coll Chem, Minist Educ, Key Lab Green Chem & Technol, Chengdu 610064, Sichuan, Peoples R China

[2] Jining Med Coll, Jining 272067, Peoples R China

[3] Sichuan Univ, Dept Food Engn, Chengdu 610065, Sichuan, Peoples R China

来源：

TETRAHEDRON LETTERS | 2017年 / 58卷 / 42期

基金：

中国国家自然科学基金;

关键词：

Botryolide-E; Epimer; Natural product; Synthesis; gamma-Lactone; METHYLENE-GAMMA-BUTYROLACTONES; STEREOSELECTIVE TOTAL-SYNTHESIS; BOTRYOLIDE-E; BIOLOGICAL EVALUATION; ASYMMETRIC-SYNTHESIS; ANALOGS; BUTENOLIDES; INHIBITION;

D O I：

10.1016/j.tetlet.2017.08.057

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first synthesis of (+)-botryolide-E and its C-7 epimer has been achieved in 8 steps from o-Glucono-3lactone, and their antibiotic activities were also investigated preliminarily. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：3947 / 3950

页数：4

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