A concise synthesis of (+)-botryolide-E and its C-7 epimer

被引：9
|
作者：
Liu, Xiaojing [1 ]
Chen, Ruijiao [1 ,2 ]
Duan, Feixia [3 ]
Jia, Junhao [1 ]
Zhou, Yuqin [1 ]
Chen, Xiaochuan [1 ]
机构：
[1] Sichuan Univ, Coll Chem, Minist Educ, Key Lab Green Chem & Technol, Chengdu 610064, Sichuan, Peoples R China
[2] Jining Med Coll, Jining 272067, Peoples R China
[3] Sichuan Univ, Dept Food Engn, Chengdu 610065, Sichuan, Peoples R China
来源：
TETRAHEDRON LETTERS | 2017年 / 58卷 / 42期
基金：
中国国家自然科学基金;
关键词：
Botryolide-E; Epimer; Natural product; Synthesis; gamma-Lactone; METHYLENE-GAMMA-BUTYROLACTONES; STEREOSELECTIVE TOTAL-SYNTHESIS; BOTRYOLIDE-E; BIOLOGICAL EVALUATION; ASYMMETRIC-SYNTHESIS; ANALOGS; BUTENOLIDES; INHIBITION;
D O I：
10.1016/j.tetlet.2017.08.057
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The first synthesis of (+)-botryolide-E and its C-7 epimer has been achieved in 8 steps from o-Glucono-3lactone, and their antibiotic activities were also investigated preliminarily. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3947 / 3950
页数：4
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