BCLC strategy for prognosis prediction and treatment recommendation: The 2022 update

被引：2601

作者：

Reig, Maria ^{[1
,2
]}

Forner, Alejandro ^{[1
,2
]}

Rimola, Jordi ^{[3
]}

Ferrer-Fabrega, Joana ^{[4
]}

Burrel, Marta ^{[5
]}

Garcia-Criado, Angeles ^{[3
]}

Kelley, Robin K. ^{[6
]}

Galle, Peter R. ^{[7
]}

Mazzaferro, Vincenzo ^{[8
,9
]}

Salem, Riad ^{[10
]}

Sangro, Bruno ^{[2
,11
]}

Singal, Amit G. ^{[12
]}

Vogel, Arndt ^{[13
]}

Fuster, Josep ^{[2
,4
]}

Ayuso, Carmen ^{[2
,3
]}

Bruix, Jordi ^{[1
,2
]}

机构：

[1] Univ Barcelona, Hosp Clin Barcelona, IDIBAPS, BCLC Grp,Liver Unit,ICMDM, Barcelona, Spain

[2] Ctr Invest Biomed Red Enfermedades Hepat & Digest, Barcelona, Spain

[3] Univ Barcelona, Hosp Clin Barcelona, CDI, BCLC Grp,Radiol Dept, Barcelona, Spain

[4] Univ Barcelona, Hosp Clin Barcelona, IDIBAPS, BCLC Grp,Surg Dept,ICMDM, Barcelona, Spain

[5] Univ Barcelona, BCLC Grp, Vasc Dept, CDI,Hosp Clin Barcelona,Barcelona Univ, Barcelona, Spain

[6] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA

[7] Mainz Univ, Dept Internal Med, Med Ctr, Mainz, Germany

[8] Univ Milan, Dept Oncol, Milan, Italy

[9] Fdn IRCCS Ist Nazl Tumori, HPB Surg & Liver Transplantat, Milan, Italy

[10] Northwestern Univ, Dept Radiol, Sect Intervent Radiol, Chicago, IL USA

[11] Clin Univ Navarra, Liver Unit, Pamplona, Spain

[12] Univ Texas Southwestern Med Ctr Dallas, Dept Internal Med, Dallas, TX USA

[13] Hannover Med Sch, Dept Gastroenterol Hepatol & Endocrinol, Hannover, Germany

来源：

JOURNAL OF HEPATOLOGY | 2022年 / 76卷 / 03期

关键词：

HCC; survival; BCLC; ablation; surgery; liver transplantation TACE; TARE; systemic treatment; ALBI score; AFP; RANDOMIZED CONTROLLED-TRIAL; UNRESECTABLE HEPATOCELLULAR-CARCINOMA; CLINICAL DECISION-MAKING; OPEN LIVER RESECTION; RADIOFREQUENCY ABLATION; TRANSARTERIAL CHEMOEMBOLIZATION; ALPHA-FETOPROTEIN; SURGICAL RESECTION; HEPATIC RESECTION; PORTAL-HYPERTENSION;

D O I：

10.1016/j.jhep.2021.11.018

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

There have been major advances in the armamentarium for hepatocellular carcinoma (HCC) since the last official update of the Barcelona Clinic Liver Cancer prognosis and treatment strategy published in 2018. Whilst there have been advances in all areas, we will focus on those that have led to a change in strategy and we will discuss why, despite being encouraging, data for select interventions are still too immature for them to be incorporated into an evidence-based model for clinicians and researchers. Finally, we describe the critical insight and expert knowledge that are required to make clinical decisions for individual patients, considering all of the parameters that must be considered to deliver personalised clinical management. (C) 2021 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.

引用

页码：681 / 693

页数：13

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