Mechanical and electrical properties of red blood cells using optical tweezers

被引：17

作者：

Fontes, A. ^{[1
]}

Barjas Castro, M. L. ^{[2
]}

Brandao, M. M. ^{[2
]}

Fernandes, H. P. ^{[2
]}

Thomaz, A. A. ^{[3
]}

Huruta, R. R. ^{[2
]}

Pozzo, L. Y. ^{[3
]}

Barbosa, L. C. ^{[3
]}

Costa, F. F. ^{[2
]}

Saad, S. T. O. ^{[2
]}

Cesar, C. L. ^{[3
]}

机构：

[1] Univ Fed Pernambuco, Dept Biofis & Radiobiol, BR-50670901 Recife, PE, Brazil

[2] Univ Estadual Campinas, Hematol & Transfus Ctr, BR-13083878 Campinas, SP, Brazil

[3] Univ Estadual Campinas, Inst Fis Gleb Wataghin, BR-13083859 Campinas, SP, Brazil

来源：

JOURNAL OF OPTICS | 2011年 / 13卷 / 04期

关键词：

optical tweezers; red blood cells; mechanical properties; electrical properties; SICKLE ERYTHROCYTES; SURFACE CHARGE; DEFORMABILITY; DEFORMATION; FORCES; VISCOSITY; DISEASE;

D O I：

10.1088/2040-8978/13/4/044012

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

Optical tweezers are a very sensitive tool, based on photon momentum transfer, for individual, cell by cell, manipulation and measurements, which can be applied to obtain important properties of erythrocytes for clinical and research purposes. Mechanical and electrical properties of erythrocytes are critical parameters for stored cells in transfusion centers, immunohematological tests performed in transfusional routines and in blood diseases. In this work, we showed methods, based on optical tweezers, to study red blood cells and applied them to measure apparent overall elasticity, apparent membrane viscosity, zeta potential, thickness of the double layer of electrical charges and adhesion in red blood cells.

引用

页数：8

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