Matrix modeling and remodeling: A biological interplay regulating tissue homeostasis and diseases

被引:177
作者
Karamanos, Nikos K. [1 ]
Theocharis, Achilleas D. [1 ]
Neill, Thomas [2 ]
Iozzo, Renato V. [2 ]
机构
[1] Univ Patras, Dept Chem, Biochem Biochem Anal & Matrix Pathobiochem Res Gr, Lab Biochem, Patras 26500, Greece
[2] Thomas Jefferson Univ, Dept Pathol Anat & Cell Biol, Canc Cell Biol & Signaling Program, Sidney Kimmel Med Coll, Philadelphia, PA 19107 USA
基金
美国国家卫生研究院;
关键词
Proteoglycans; Collagens; Proteases; Senescence; Cancer; EXTRACELLULAR-MATRIX; BASEMENT-MEMBRANE; HEPARAN-SULFATE; MECHANICAL-PROPERTIES; CYSTEINE CATHEPSINS; ANGIOSTATIC MODULE; ENDOTHELIAL-CELLS; CANCER GROWTH; IN-VITRO; COLLAGEN;
D O I
10.1016/j.matbio.2018.08.007
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The overall structure and architecture of the extracellular matrix undergo dramatic alterations in composition, form, and functionality over time. The stochasticity begins during development, essential for maintaining organismal homeostasis and is heavily implicated in many pathobiological states including fibrosis and cancer. Modeling and remodeling of the matrix is driven by the local cellular milieu and secreted and cell-associated components in a framework of dynamic reciprocity. This collection of expertly-written reviews aims to relay state-of-the-art information concerning the mechanisms of matrix modeling and remodeling in physiological development and disease. (C) 2018 Elsevier B.V. All rights reserved.
引用
收藏
页码:1 / 11
页数:11
相关论文
共 137 条
[1]   Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis [J].
Agrawal, S ;
Anderson, P ;
Durbeej, M ;
van Rooijen, N ;
Ivars, F ;
Opdenakker, G ;
Sorokin, LM .
JOURNAL OF EXPERIMENTAL MEDICINE, 2006, 203 (04) :1007-1019
[2]   Structural basis of collagen fiber degradation by cathepsin K [J].
Aguda, Adeleke H. ;
Panwar, Preety ;
Du, Xin ;
Nguyen, Nham T. ;
Brayer, Gary D. ;
Broemme, Dieter .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (49) :17474-17479
[3]   Cathepsin B activity regulation - Heparin-like glycosaminoglycans protect human cathepsin B from alkaline pH-induced inactivation [J].
Almeida, PC ;
Nantes, IL ;
Chagas, JR ;
Rizzi, CCA ;
Faljoni-Alario, A ;
Carmona, E ;
Juliano, L ;
Nader, HB ;
Tersariol, ILS .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (02) :944-951
[4]   BIOSYNTHETIC AND PROLIFERATIVE CHARACTERISTICS OF TUBULOINTERSTITIAL FIBROBLASTS PROBED WITH PARACRINE CYTOKINES [J].
ALVAREZ, RJ ;
SUN, MJ ;
HAVERTY, TP ;
IOZZO, RV ;
MYERS, JC ;
NEILSON, EG .
KIDNEY INTERNATIONAL, 1992, 41 (01) :14-23
[5]   Metalloproteinases: A parade of functions in matrix biology and an outlook for the future [J].
Apte, Suneel S. ;
Parks, William C. .
MATRIX BIOLOGY, 2015, 44-46 :1-6
[6]   The role of TIMPs in regulation of extracellular matrix proteolysis [J].
Arpino, Valerie ;
Brock, Michael ;
Gill, Sean E. .
MATRIX BIOLOGY, 2015, 44-46 :247-254
[7]   Regulation of senescence associated signaling mechanisms in chondrocytes for cartilage tissue regeneration [J].
Ashraf, S. ;
Cha, B. -H. ;
Kim, J. -S. ;
Ahn, J. ;
Han, I. ;
Park, H. ;
Lee, S. -H. .
OSTEOARTHRITIS AND CARTILAGE, 2016, 24 (02) :196-205
[8]   Chemotherapy induces secretion of exosomes loaded with heparanase that degrades extracellular matrix and impacts tumor and host cell behavior [J].
Bandari, Shyam K. ;
Purushothaman, Anurag ;
Ramani, Vishnu C. ;
Brinkley, Garrett J. ;
Chandrashekar, Darshan S. ;
Varambally, Sooryanarayana ;
Mobley, James A. ;
Zhang, Yi ;
Brown, Elizabeth E. ;
Vlodavsky, Israel ;
Sanderson, Ralph D. .
MATRIX BIOLOGY, 2018, 65 :104-118
[9]   The provisional matrix: setting the stage for tissue repair outcomes [J].
Barker, Thomas H. ;
Engler, Adam J. .
MATRIX BIOLOGY, 2017, 60-61 :1-4
[10]   Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation [J].
Bi, Xiuli ;
Tong, Chang ;
Dockendorff, Ashley ;
Bancroft, Laura ;
Gallagher, Lindsay ;
Guzman, Grace ;
Iozzo, Renato V. ;
Augenlicht, Leonard H. ;
Yang, Wancai .
CARCINOGENESIS, 2008, 29 (07) :1435-1440