Bioapplications of light-sensitive polymer films and capsules assembled using the layer-by-layer technique

被引：59

作者：

Volodkin, Dmitry ^{[1
]}

Skirtach, Andre ^{[2
,3
,4
]}

Moehwald, Helmuth ^{[2
]}

机构：

[1] Fraunhofer Inst Biomed Engn IBMT, Dept Cellular Biotechnol & Biochips, D-14424 Golm, Germany

[2] Max Planck Inst Colloids & Interfaces, Dept Interfaces, D-14424 Golm, Germany

[3] Univ Ghent, Dept Mol Biotechnol, B-9000 Ghent, Belgium

[4] Univ Ghent, NB Photon, B-9000 Ghent, Belgium

来源：

POLYMER INTERNATIONAL | 2012年 / 61卷 / 05期

关键词：

multilayer; polyelectrolyte; laser; release; bioactive; POLYELECTROLYTE MULTILAYER FILMS; CLASS-I MOLECULES; THIN-FILMS; DRUG-DELIVERY; BIOMEDICAL APPLICATIONS; ENCAPSULATED MATERIALS; SECONDARY STRUCTURE; GOLD NANOPARTICLES; REMOTE RELEASE; MICROCAPSULES;

D O I：

10.1002/pi.4182

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

This review covers the area of bioapplications of layer-by-layer assembled polymer planar films and microcapsulesbiologically relevant responses stimulated by light. We present recent progress in light-stimulated release of bioactive molecules from the assembled structures. Functionalization of the films with metal nanoparticles and bioactive molecules that provide the films with light sensitivity and reservoir properties is also described. The use of these films in the delivery of bioactive molecules is closely related to light-induced cargo release from capsules; this promising method of intracellular delivery is also addressed. Copyright (c) 2012 Society of Chemical Industry

引用

页码：673 / 679

页数：7