Ligand-induced acceleration of the intramolecular [3+2] cycloaddition between alkynes and alkylidenecyclopropanes

被引：48
作者：
Durán, J [1 ]
Gulías, M [1 ]
Castedo, L [1 ]
Mascareñas, JL [1 ]
机构：
[1] Univ Santiago de Compostela, Unidad Asociada CSIC, Dept Quim Organ, Santiago De Compostela 15782, Spain
来源：
ORGANIC LETTERS | 2005年 / 7卷 / 25期
关键词：
D O I：
10.1021/ol0524095
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Bulky phosphite L-6 and several sterically robust phosphoramidites are excellent ligands for promoting the Pd-catalyzed [3 + 2] intramolecular cycloaddition between alkylidenecyclopropanes and alkynes. The use of these ligands allows for low catalyst loadings and facilitates the otherwise sluggish cycloaddition of hept-6-ynylidenecyclopropane systems.
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收藏
页码：5693 / 5696
页数：4
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