Stem cells in the umbilical cord

被引：295
|
作者：
Weiss, Mark L. [1 ]
Troyer, Deryl L.
机构：
[1] Kansas State Univ, Dept Anat & Physiol, Coll Vet Med, Manhattan, KS 66506 USA
来源：
STEM CELL REVIEWS | 2006年 / 2卷 / 02期
基金：
美国国家卫生研究院;
关键词：
umbilical cord matrix cells; Wharton's Jelly; mesenchymal stem cells; umbilical cord blood cells;
D O I：
10.1007/s12015-006-0022-y
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Stem cells are the next frontier in medicine. Stem cells are thought to have great therapeutic and biotechnological potential. This will not only to replace damaged or dysfunctional cells, but also rescue them and/or deliver therapeutic proteins after they have been engineered to do so. Currently, ethical and scientific issues surround both embryonic and fetal stem cells and hinder their widespread implementation. In contrast, stem cells recovered postnatally from the umbilical cord, including the umbilical cord blood cells, amnion/placenta, umbilical cord vein, or umbilical cord matrix cells, are a readily available and inexpensive source of cells that are capable of forming many different cell types (i.e., they are "multipotent"). This review will focus on the umbilical cord-derived stem cells and compare those cells with adult bone marrow-derived mesenchymal stem cells.
引用
收藏
页码：155 / 162
页数：8
相关论文
共 50 条
  • [31] Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury
    CAO Fujiang and FENG Shiqing Department of OrthopaedicsGeneral Hospital of Tianjin Medical UniversityTianjin China
    中华医学杂志（英文版）, 2009, (02) : 225 - 231
  • [32] Transplantation of Umbilical Cord Blood Stem Cells for Treating Spinal Cord Injury
    Dong-Hyuk Park
    Jeong-Hyun Lee
    Cesario V. Borlongan
    Paul R. Sanberg
    Yong-Gu Chung
    Tai-Hyoung Cho
    Stem Cell Reviews and Reports, 2011, 7 : 181 - 194
  • [33] Transplantation of Umbilical Cord Blood Stem Cells for Treating Spinal Cord Injury
    Park, Dong-Hyuk
    Lee, Jeong-Hyun
    Borlongan, Cesario V.
    Sanberg, Paul R.
    Chung, Yong-Gu
    Cho, Tai-Hyoung
    STEM CELL REVIEWS AND REPORTS, 2011, 7 (01) : 181 - 194
  • [34] Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury
    Fu-jiang, Cao
    Shi-qing, Feng
    CHINESE MEDICAL JOURNAL, 2009, 122 (02) : 225 - 231
  • [35] Multipotent stem cells from umbilical cord:: Cord is richer than blood!
    Secco, Mariane
    Zucconi, Eder
    Vieira, Natassia M.
    Fogaca, Luciana L. Q.
    Cerqueira, Antonia
    Carvalho, Maria Denise F.
    Jazedje, Tatiana
    Okamoto, Oswaldo K.
    Muotri, Alysson R.
    Zatz, Mayana
    STEM CELLS, 2008, 26 (01) : 146 - 150
  • [36] Application of Human Umbilical Cord Mesenchymal Stem Cells in Spinal Cord Injury
    Yang, Peng
    Li, Yun
    Zhang, Jing-Tao
    Wang, Lin-Feng
    Shen, Yong
    JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING, 2017, 7 (05) : 393 - 400
  • [37] Umbilical cord mesenchymal stem cells increase expansion of cord blood natural killer cells
    Boissel, Laurent
    Tuncer, Hande H.
    Betancur, Monica
    Wolfberg, Adam
    Klingemann, Hans
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2008, 14 (09) : 1031 - 1038
  • [38] Umbilical cord blood stem cells-derived microglia
    Takahashi, K.
    Yamazaki, H.
    Yamada, M.
    GLIA, 2015, 63 : E89 - E90
  • [39] Improving umbilical cord blood stem cells for transplantation.
    Sanberg, P. R.
    Sanberg, C. D.
    Kuzmenok, O.
    Kuzmin-Nichols, N.
    Godard, G.
    Amaratunga, M.
    Bork, S.
    CYTOTHERAPY, 2006, 8
  • [40] Application of Umbilical Cord Blood Stem Cells in Regenerative Medicine
    Meiliana, Anna
    Wijaya, Andi
    INDONESIAN BIOMEDICAL JOURNAL, 2014, 6 (03): : 115 - 122
12345